WEBVTT 00:00.000 --> 00:27.000 This is dedicated to all the Hackers and the Crackers 00:27.000 --> 00:29.000 To the Hackers and the Crackers 00:29.000 --> 00:32.000 I see in binary, I speak source code 00:32.000 --> 00:36.000 Step on my toes, I'll post a million jpegs if you're in a fag pone 00:36.000 --> 00:38.000 In your digital stance, getting firewalled ho 00:38.000 --> 00:41.000 Cause I'm riding the net in my 6-4 00:41.000 --> 00:43.000 I was a dick with my 56 00:43.000 --> 00:46.000 Now with my cable, I'm able to get that stable 00:46.000 --> 00:48.000 On the out, my name is Ace and I'm a Leo 00:48.000 --> 00:52.000 On the digital highway, my name is Neo and I'm a hero 00:52.000 --> 00:54.000 In a flash, I'll screw you on burning dreamcast 00:54.000 --> 00:57.000 You need some ISO? Let me through my hard drive rifle 00:57.000 --> 00:59.000 Our exchange you could never stifle 00:59.000 --> 01:02.000 In a digital hug, you just caught the love bug 01:02.000 --> 01:04.000 I bootlegged your CD 01:04.000 --> 01:06.000 I caused a fight between Un and Jay-Z 01:06.000 --> 01:08.000 Your CG, it's all gonna be free 01:08.000 --> 01:11.000 Whether we take it by force or we take it nicely 01:11.000 --> 01:13.000 You feel that rattle in your bones 01:13.000 --> 01:15.000 When I tell you we just hacked out Jones 01:15.000 --> 01:17.000 And NASDAQ leaves you flat on your back 01:17.000 --> 01:19.000 Cause I am he who loves to hack and crack 01:19.000 --> 01:22.000 Cause I am he who loves to hack and crack 01:22.000 --> 01:26.000 This is dedicated to the hackers and the criminals 01:26.000 --> 01:29.000 Serial phones, source codes, ISO 01:29.000 --> 01:32.000 Hello and welcome to Binary Revolution Radio 01:32.000 --> 01:34.000 Episode number 1414 01:34.000 --> 01:35.000 March 28th, 2006 01:35.000 --> 01:37.000 I'm Strom Carlson 01:37.000 --> 01:39.000 I'm Black Ratchet 01:39.000 --> 01:42.000 And this evening we have with us is Dr. Zygmunt again 01:42.000 --> 01:43.000 Two weeks in a row 01:43.000 --> 01:46.000 Wow, yeah, I guess I'm just a lucky guy 01:46.000 --> 01:48.000 Yeah, you're just really cool and everything 01:48.000 --> 01:50.000 With the whole getting in there 01:50.000 --> 01:51.000 And setting everything up 01:51.000 --> 01:53.000 And not having to answer phone calls 01:53.000 --> 01:55.000 And that kind of stuff 01:55.000 --> 01:57.000 Yeah, you know what I think it really comes down to 01:57.000 --> 01:59.000 Is I kind of live on IRC 01:59.000 --> 02:03.000 So you kind of just constantly exposed to my banter 02:03.000 --> 02:05.000 And you have no choice but to succumb 02:05.000 --> 02:07.000 And invite me onto the show 02:07.000 --> 02:08.000 Exactly, man 02:08.000 --> 02:09.000 I tried to get on the show 02:09.000 --> 02:10.000 And like I was thinking 02:10.000 --> 02:12.000 Man, I can't have Dr. Zygmunt on this week 02:12.000 --> 02:14.000 And then I started going into like twitches 02:14.000 --> 02:15.000 And getting to shoot chills 02:15.000 --> 02:17.000 It was like, oh man 02:17.000 --> 02:18.000 But you're here now 02:18.000 --> 02:19.000 So that's good 02:19.000 --> 02:22.000 Yeah, sure, whatever 02:22.000 --> 02:25.000 I guess you could kind of 02:25.000 --> 02:27.000 We have a subtitle over this episode 02:27.000 --> 02:29.000 This is Episode 141 02:29.000 --> 02:31.000 When Bad Servers Attack 02:31.000 --> 02:33.000 Oh yeah 02:33.000 --> 02:35.000 Yeah, I don't know what happened 02:35.000 --> 02:38.000 It's like the dreaded Voipocalypse came about today 02:39.000 --> 02:44.000 What was that 141 in the old KP style? 02:44.000 --> 02:45.000 Oh yeah 02:45.000 --> 02:46.000 The rooting codes 02:46.000 --> 02:47.000 We'll see 02:47.000 --> 02:48.000 121 was inward 02:48.000 --> 02:49.000 131 is directory 02:49.000 --> 02:50.000 I forget what 02:50.000 --> 02:52.000 I think 141 might be rate and root 02:52.000 --> 02:53.000 Yeah, that sounds right 02:53.000 --> 02:54.000 Hold on 02:54.000 --> 02:55.000 We'll have to actually look this up 02:55.000 --> 02:57.000 Are we going to have that fight again? 02:57.000 --> 02:59.000 KP 141 02:59.000 --> 03:00.000 KP 141 03:00.000 --> 03:01.000 Let's start 03:03.000 --> 03:04.000 ST 03:04.000 --> 03:06.000 So we start at 2600 03:06.000 --> 03:07.000 Meeeeee 03:07.000 --> 03:08.000 Yep, routing 03:08.000 --> 03:09.000 Ooh, very good, Strom 03:09.000 --> 03:10.000 You get an A-plus this evening 03:10.000 --> 03:11.000 Yay 03:11.000 --> 03:15.000 So it only followed that we'd be having rooting problems tonight, right? 03:15.000 --> 03:16.000 Well it wasn't 03:16.000 --> 03:18.000 I don't know what the hell was going on 03:18.000 --> 03:19.000 Like 03:19.000 --> 03:20.000 Well for example 03:20.000 --> 03:21.000 We suddenly couldn't like 03:21.000 --> 03:22.000 I couldn't 03:22.000 --> 03:25.000 Dial into the bridge on Strom's computer 03:25.000 --> 03:26.000 And we're going 03:26.000 --> 03:27.000 Okay, so 03:27.000 --> 03:28.000 I got on the bridge 03:28.000 --> 03:30.000 And then I was going to conference Zygmunt on 03:30.000 --> 03:31.000 And then all of a sudden 03:31.000 --> 03:32.000 New phone was started acting up 03:32.000 --> 03:33.000 Like 03:33.000 --> 03:35.000 Your phone did ring, Zygmunt, right? 03:35.000 --> 03:37.000 It did, and then I got a dial tone 03:37.000 --> 03:38.000 Yeah 03:38.000 --> 03:39.000 Which was nice 03:39.000 --> 03:42.000 Yeah, and I couldn't actually use one of my alternate providers 03:42.000 --> 03:44.000 Because I just didn't have that set up on my phone correctly 03:44.000 --> 03:46.000 Which is something I'm waiting to have to look into 03:46.000 --> 03:47.000 And 03:47.000 --> 03:48.000 Ugh 03:49.000 --> 03:50.000 It may have to do with the fact that 03:50.000 --> 03:51.000 But we are here 03:51.000 --> 03:54.000 I just recently upgraded my asterisk box to 1.2.5 03:54.000 --> 03:56.000 Although I don't think that would cause any problems 03:58.000 --> 03:59.000 I mean, it is stable after all 03:59.000 --> 04:02.000 This is a big change from the 1.0 series to the 1.2 series 04:02.000 --> 04:03.000 Well yeah, no, but I went from one 04:03.000 --> 04:04.000 Especially in the output on the console 04:04.000 --> 04:06.000 Yeah, but I was running 1.2.4 last week 04:06.000 --> 04:08.000 Oh, that's not a big thing then 04:08.000 --> 04:09.000 Yeah 04:09.000 --> 04:11.000 I've known that you'd be up to date on your asterisk version 04:12.000 --> 04:13.000 Screw you all 04:13.000 --> 04:14.000 I'm still running subversion 04:14.000 --> 04:16.000 They actually fixed the Eek's bug 04:16.000 --> 04:17.000 Just in case anyone's curious 04:17.000 --> 04:18.000 Oh, did they? 04:18.000 --> 04:19.000 Okay, good, I can go back to that then 04:19.000 --> 04:20.000 Yeah 04:20.000 --> 04:22.000 I was running Bleeding Edge for a while 04:22.000 --> 04:24.000 At least I assumed they fixed the Eek's bug 04:24.000 --> 04:25.000 That could be the problem tonight 04:25.000 --> 04:26.000 But 04:26.000 --> 04:28.000 Well, it wouldn't have gotten to stable, would it? 04:29.000 --> 04:30.000 Well, no, no, no 04:30.000 --> 04:31.000 What the weird part is 04:31.000 --> 04:33.000 Like, last night I was actually 04:34.000 --> 04:36.000 I was trying to verify some payphones for Yapple 04:36.000 --> 04:37.000 Yeah 04:37.000 --> 04:41.000 And the, you know, my Eek's trunks kept on, you know, really getting messed up 04:41.000 --> 04:42.000 So I was like, okay, fine 04:42.000 --> 04:44.000 We'll just, you know, redo it right here, right now 04:44.000 --> 04:46.000 And it seemed to be working fine 04:46.000 --> 04:47.000 So I assumed the bug was fixed 04:47.000 --> 04:48.000 But 04:49.000 --> 04:50.000 Who knows? 04:50.000 --> 04:51.000 Maybe it was me again 04:51.000 --> 04:53.000 And all this stuff is causing issues and everything 04:53.000 --> 04:54.000 Might be 04:54.000 --> 04:55.000 Maybe we just got lucky 04:55.000 --> 04:57.000 Or unload 04:57.000 --> 04:58.000 Well, technically we did get lucky 04:58.000 --> 04:59.000 So thank goodness 04:59.000 --> 05:00.000 Yeah 05:00.000 --> 05:01.000 That we actually got on the air 05:01.000 --> 05:02.000 So 05:02.000 --> 05:03.000 What did you guys have to spare? 05:03.000 --> 05:04.000 Like three seconds? 05:05.000 --> 05:06.000 Fifteen, I believe the song started 05:07.000 --> 05:08.000 Um, something like that 05:08.000 --> 05:09.000 I mean, actually what happened was 05:09.000 --> 05:10.000 I saw 05:10.000 --> 05:11.000 Just before I started the music 05:11.000 --> 05:12.000 I saw the 05:13.000 --> 05:15.000 The streaming app that goes from 05:16.000 --> 05:17.000 From my computer out to the 05:17.000 --> 05:18.000 The hack radio server 05:18.000 --> 05:20.000 I saw it drop and then reconnect 05:21.000 --> 05:22.000 Oh, wow 05:22.000 --> 05:23.000 So I was like, whoops 05:23.000 --> 05:24.000 Crap, yeah 05:24.000 --> 05:26.000 I was literally tuning in 05:26.000 --> 05:28.000 And making sure that we were in fact streaming live 05:28.000 --> 05:29.000 So I didn't have to say 05:29.000 --> 05:30.000 Oh, hey, guess what guys? 05:30.000 --> 05:32.000 It's playing last week's episode 05:33.000 --> 05:34.000 Well, you know, whatever 05:34.000 --> 05:35.000 Is it Murphy's Law? 05:35.000 --> 05:36.000 Anything that can go wrong, Will? 05:37.000 --> 05:38.000 Yeah, something like that 05:39.000 --> 05:40.000 Actually, um 05:41.000 --> 05:43.000 Well, since we're talking about Murphy's Law 05:43.000 --> 05:45.000 The Murphy's Law is not 05:46.000 --> 05:47.000 Whatever can go wrong, Will 05:47.000 --> 05:49.000 That's actually Finagle's Law 05:49.000 --> 05:50.000 Oh, sorry 05:50.000 --> 05:52.000 Murphy's Law is 05:52.000 --> 05:53.000 Oh, shoot 05:53.000 --> 05:54.000 I forgot the actual text 05:54.000 --> 05:55.000 It's like 05:55.000 --> 05:57.000 If there's one of two ways 05:57.000 --> 05:58.000 Someone can put 05:58.000 --> 05:59.000 Someone can do something 05:59.000 --> 06:00.000 They'll always do it the wrong way 06:01.000 --> 06:02.000 Oh, really? 06:02.000 --> 06:03.000 Yeah 06:03.000 --> 06:04.000 According to 06:04.000 --> 06:05.000 Murphy's Law 06:05.000 --> 06:06.000 Also known as Finagle's Law 06:06.000 --> 06:07.000 Or Sod's Law 06:08.000 --> 06:10.000 Is a popular adage in Western culture 06:10.000 --> 06:11.000 Which broadly states that 06:11.000 --> 06:14.000 Things will go wrong in any given situation 06:16.000 --> 06:17.000 Well, you can't have a chat about Murphy's Law 06:17.000 --> 06:19.000 Without talking about Occam's Razor 06:19.000 --> 06:20.000 At the same time 06:21.000 --> 06:22.000 That's true 06:23.000 --> 06:24.000 Everybody saw, uh, what was the movie? 06:24.000 --> 06:25.000 Contact? 06:26.000 --> 06:27.000 Yeah, well, the simplest solution 06:27.000 --> 06:28.000 Tends to be the best one 06:28.000 --> 06:29.000 All other things being equal 06:31.000 --> 06:33.000 Yeah, gotta have love for all your laws 06:35.000 --> 06:36.000 Remember, kids 06:37.000 --> 06:38.000 Whatever will go wrong can go wrong 06:38.000 --> 06:39.000 Not just a good idea 06:39.000 --> 06:40.000 It's a law 06:41.000 --> 06:42.000 Exactly 06:42.000 --> 06:43.000 Exactly 06:43.000 --> 06:45.000 Are you gonna have McGruff say it next? 06:46.000 --> 06:48.000 Only you can take a bite out of 06:48.000 --> 06:49.000 Telephony 06:49.000 --> 06:50.000 Probability statistics 06:51.000 --> 06:52.000 Statistical probabilities 06:53.000 --> 06:54.000 Exact 06:54.000 --> 06:55.000 Bad weight routing statistics 06:55.000 --> 06:56.000 Rawr 06:57.000 --> 06:59.000 Only you can fundamentally restructure 06:59.000 --> 07:01.000 The nature of mathematics 07:01.000 --> 07:02.000 So 07:02.000 --> 07:06.000 It wouldn't be too hard, right? 07:06.000 --> 07:07.000 No? 07:08.000 --> 07:09.000 How many, how many, uh 07:10.000 --> 07:11.000 Oh, let's not get into that 07:11.000 --> 07:12.000 That'll take 20 minutes to get through 07:13.000 --> 07:16.000 The difference between Cartesian and non-Cartesian mathematics 07:17.000 --> 07:18.000 Yeah, so anyway 07:19.000 --> 07:20.000 In housekeeping 07:22.000 --> 07:24.000 Despite all the problems we're having right now 07:24.000 --> 07:26.000 I did go to great lengths to 07:26.000 --> 07:29.000 To set things up, uh, well for our toll-free number 07:30.000 --> 07:32.000 Which now, when you call it during the show 07:33.000 --> 07:36.000 Roots you to, uh, to Zygmunt if he's answering the phones 07:37.000 --> 07:39.000 And if you call it not during the show 07:39.000 --> 07:41.000 It automatically roots you to our voicemail box 07:44.000 --> 07:47.000 So you can now, uh, you can now call us at any time 07:47.000 --> 07:49.000 And it will reach you to the correct place based on the hour of the day 07:50.000 --> 07:52.000 Ooooooo 07:52.000 --> 07:54.000 And also, due to, due to popular demand 07:55.000 --> 07:57.000 And by popular demand, I mean, I heard three people fetching about it 07:58.000 --> 08:00.000 We have a free world dial-up number down as well 08:01.000 --> 08:02.000 Oh, what's our free world dial-up number? 08:03.000 --> 08:04.000 Help to include that in the shoe notes 08:04.000 --> 08:05.000 Um, let me see, I put everything up 08:06.000 --> 08:08.000 There's a post on the, on the bin rev forums actually 08:09.000 --> 08:11.000 Under, uh, I made it a sticky under hacker media 08:12.000 --> 08:14.000 Oh, you mean people actually go to the bin rev forums? 08:15.000 --> 08:16.000 I mean, I don't 08:17.000 --> 08:18.000 Yeah, well you're looking that up 08:18.000 --> 08:22.000 Anyway, our normal, our normal call-in is 888-9-BINREV 08:23.000 --> 08:25.000 Right, and our free world dial-up number is 758-103 08:27.000 --> 08:29.000 Oh, six digits, I thought they were up to like seven now or something 08:30.000 --> 08:31.000 No, no, no, wait 08:32.000 --> 08:33.000 Yeah, six digits starting with seven 08:34.000 --> 08:35.000 Yeah, I have a five-digit, I believe 08:36.000 --> 08:37.000 Yeah, I've got a five-digit too 08:38.000 --> 08:39.000 Oh, aren't you guys classic? 08:40.000 --> 08:41.000 It's like, it's like slash dot user IDs, you know 08:42.000 --> 08:44.000 My user ID is lower than your, therefore my fellows is larger 08:44.000 --> 08:47.000 That sums up slash dot pretty well 08:48.000 --> 08:49.000 Yeah 08:50.000 --> 08:56.000 Um, our UK call-in, which I assume still works, is 0845-646-0102 08:57.000 --> 09:01.000 Yeah, and what I actually will do is sometime between now and soon 09:02.000 --> 09:06.000 I'll get a call-in number that goes directly to our box so I can verify that it works 09:07.000 --> 09:09.000 And I will post that number as well 09:09.000 --> 09:14.000 Well, yeah, well, you just need to talk to the guy, I think he talked about setting it up directly in or something 09:15.000 --> 09:16.000 Okay, or someone else, who cares? 09:18.000 --> 09:23.000 Anyway, do we have any other housekeeping type things going on? 09:24.000 --> 09:28.000 That I think is it, I'm just relieved that we're actually casting live now 09:29.000 --> 09:30.000 You're not the only one 09:31.000 --> 09:36.000 Yeah, and of course this is the week that both, you know, Strom decides to show up ten minutes before the episode 09:36.000 --> 09:38.000 Hey, I didn't decide that 09:39.000 --> 09:40.000 Well, I'm sorry, I'm sorry 09:40.000 --> 09:43.000 L.A. traffic dictated to Strom that he show up ten minutes before the episode 09:43.000 --> 09:44.000 Yeah 09:44.000 --> 09:48.000 And, you know, I was sidelined enough that I had to show up fifteen minutes before the episode 09:48.000 --> 09:53.000 So therefore, like, I couldn't suddenly get on the bridge and I have to pin it on him as soon as he shows up 09:53.000 --> 09:54.000 And I'm like, ah! 09:55.000 --> 09:57.000 I was ready, for the record 09:57.000 --> 09:58.000 Yeah, you were ready 09:58.000 --> 09:59.000 Yeah, we'll use that 09:59.000 --> 10:00.000 Yeah, we'll use that 10:00.000 --> 10:01.000 Yeah, we'll use that 10:01.000 --> 10:02.000 He wants the most well-prepared 10:02.000 --> 10:03.000 Alright 10:03.000 --> 10:06.000 He gets his bin rev radio preparedness merit badge 10:07.000 --> 10:09.000 I only had to do five shows, nice 10:10.000 --> 10:13.000 I don't know how many shows I've really done, but isn't that how those merit badges work? 10:13.000 --> 10:14.000 You gotta do X number of things? 10:15.000 --> 10:16.000 I think so 10:16.000 --> 10:17.000 Oh, it depends 10:17.000 --> 10:19.000 I'm on a car room with my vast Boy Scout knowledge here 10:19.000 --> 10:21.000 Eagle Scout, baby, yeah! 10:21.000 --> 10:22.000 But anyway 10:23.000 --> 10:28.000 Yeah, well, no, you had, like, a requirement, like, you know, do, like, you know, X amount of things 10:28.000 --> 10:31.000 Or, well, everything had, like, a list of requirements, but some of those requirements were like 10:32.000 --> 10:37.000 Demonstrate five ways you can, you know, do, move someone's spleen in the middle of the woods or something 10:38.000 --> 10:39.000 Just stuff like that 10:40.000 --> 10:42.000 You can do that by rubbing two sticks together, right? 10:43.000 --> 10:45.000 I can start a fire by rubbing two sticks together 10:46.000 --> 10:48.000 What about taking out somebody's spleen? 10:48.000 --> 10:50.000 I can't, I can't do the spleen thing 10:50.000 --> 10:52.000 I didn't get, I didn't get the, uh, spleen removal merit badge there 10:53.000 --> 10:54.000 It's a splenectomy merit badge 10:55.000 --> 10:56.000 A splenectomy 10:57.000 --> 10:58.000 Is that what it is? 10:59.000 --> 11:00.000 A splenectomy? 11:00.000 --> 11:05.000 Well, you can attach ectomy onto anything, and it means taking out of, or excising 11:06.000 --> 11:07.000 Yeah 11:07.000 --> 11:08.000 So, a zigectomy? 11:09.000 --> 11:11.000 It's what it removes even from the episode, the zigectomy 11:12.000 --> 11:16.000 I can just press the button here and perform a zigectomy, but, uh, I wouldn't 11:16.000 --> 11:17.000 I wouldn't 11:17.000 --> 11:18.000 We probably would never be able to get reconnected 11:18.000 --> 11:19.000 Yeah, exactly 11:19.000 --> 11:20.000 Yeah, I know, tell me about it 11:21.000 --> 11:24.000 This, this, this, this, this, this, this, it's like this button on Strom's desk that says 11:24.000 --> 11:25.000 Drop Zygmunt 11:26.000 --> 11:28.000 It has a little post above it saying no 11:29.000 --> 11:31.000 No, it looks like the button, it looks like the button from Wargames 11:32.000 --> 11:35.000 It's like neon red, and it's got yellow and black stripes around it 11:36.000 --> 11:37.000 And the glass case over it, right? 11:37.000 --> 11:38.000 Exactly, the glass case with the key 11:38.000 --> 11:39.000 With the key 11:40.000 --> 11:42.000 Well, that's, that's a very good idea, Joshua 11:43.000 --> 11:53.000 Oh, I mean, I actually, I actually had like this, I, I was, I was dumpster diving 11:54.000 --> 11:56.000 I don't know, we're very veering off topic here tonight 11:56.000 --> 11:59.000 We were, I was dumpster diving, like, back in college 11:59.000 --> 12:03.000 And I found this massive board, and it had all these buttons on it 12:03.000 --> 12:06.000 And it had like, you know, the two keys, and all like the buttons you could push 12:07.000 --> 12:10.000 And the best we could actually tell it was for like, uh, some type of autoclave 12:11.000 --> 12:15.000 Or mechanical sterilization setup, because we actually found it at the biology lab 12:16.000 --> 12:18.000 But it looked very impressive in my dorm room for a while 12:19.000 --> 12:23.000 Had, had like the keys, yeah, had the keys, like the two keys on each, either side 12:23.000 --> 12:26.000 And I didn't know if you had to turn them at the same time or whatever 12:26.000 --> 12:31.000 But it had the, um, it had like, you know, the big red button with the, with the little glass thing over it 12:32.000 --> 12:34.000 That you can't press it accidentally, a little molly guard there 12:35.000 --> 12:39.000 So, uh, you were nice and sterile, unlike every other college student 12:40.000 --> 12:41.000 Yeah 12:42.000 --> 12:46.000 Actually, someone did a, someone did a study on, um, college floors, and they were actually quite clean 12:47.000 --> 12:50.000 The floors in like, college dorm rooms? 12:50.000 --> 12:57.000 Yeah, it was amazing, because they're all usually, uh, because most of the, like the freshman dorms are, uh, tile 12:57.000 --> 12:58.000 Or at least the ones that I've been to 12:59.000 --> 13:02.000 So, like, you know, just can't actually get horrible stuff on them 13:03.000 --> 13:04.000 I wonder if they planned that on purpose 13:05.000 --> 13:06.000 They're like, huh, you know what, it's their first year of college 13:07.000 --> 13:08.000 They're probably gonna be doing a lot of drinking 13:09.000 --> 13:10.000 And it's a lot easier to clean up tile 13:11.000 --> 13:12.000 I'm sure, I'm sure it is 13:12.000 --> 13:15.000 I bet you somebody somewhere has to think of factors like that 13:16.000 --> 13:17.000 Mm-hmm 13:18.000 --> 13:19.000 That'd actually be a kinda cool job 13:19.000 --> 13:21.000 Be like, hmm, what could go on, go wrong in people's first year? 13:22.000 --> 13:23.000 Let's not have any two-story buildings 13:24.000 --> 13:29.000 And, uh, you know, let's not make the windows wide enough so a couch can sit outside 13:29.000 --> 13:32.000 Actually, my freshman dorm was 13:35.000 --> 13:36.000 Your freshman dorm was what? 13:40.000 --> 13:41.000 I guess that's it for 13:41.000 --> 13:42.000 Did we lose a ratchet? 13:43.000 --> 13:44.000 Oh, no 13:45.000 --> 13:46.000 Alright, moving right along 13:46.000 --> 13:47.000 My freshman dorm 13:48.000 --> 13:51.000 Has since been totally demolished and replaced with a nice fancy one 13:52.000 --> 13:53.000 Ah, fancy, fancy 13:53.000 --> 13:56.000 Yeah, mine, uh, I didn't have, I haven't been in the dorms yet, actually 13:56.000 --> 13:59.000 That has not yet been a part of my college experience 14:00.000 --> 14:01.000 You know, that's actually a good thing 14:01.000 --> 14:02.000 We're not allowed to call them dorms at school 14:03.000 --> 14:04.000 They're residence halls 14:05.000 --> 14:06.000 You're actually not allowed to call it a dorm? 14:07.000 --> 14:08.000 No, it's a residence hall 14:09.000 --> 14:10.000 Oh, terrific 14:11.000 --> 14:12.000 They give you one of those dirty school looks 14:13.000 --> 14:14.000 Like, dang, how old are you, five? 14:17.000 --> 14:18.000 Crazy, crazy 14:19.000 --> 14:22.000 Yeah, I don't know, I, uh, I think here's a message from Ratchet 14:23.000 --> 14:24.000 Err, what happened? 14:24.000 --> 14:25.000 What happened? 14:26.000 --> 14:27.000 We lost you 14:28.000 --> 14:30.000 Well, I'll skip ahead and talk about my personal hacking story 14:31.000 --> 14:33.000 Okay, why don't you do that? I'll try and get Ratchet back 14:34.000 --> 14:35.000 That sounds like a good idea 14:36.000 --> 14:38.000 See, we were so lucky to get him so close, you just had to go 14:39.000 --> 14:42.000 Anyway, so my personal hacking story, it is going to carry over again 14:43.000 --> 14:47.000 It is about my currently vaporware version of my search engine 14:47.000 --> 14:49.000 It is getting really, really close 14:50.000 --> 14:51.000 I have the crawler, it's all nice and set up 14:52.000 --> 14:56.000 I'm hoping to release, I can't release the entire crawler because it was work for a company 14:57.000 --> 15:02.000 But I want to release just a package of the way that I parse the robots.txt file 15:02.000 --> 15:05.000 And that's something for them from the robots exclusion protocol 15:06.000 --> 15:11.000 And it's really only relevant to web crawlers and spiders 15:12.000 --> 15:13.000 And it says what they're allowed to crawl and what they're not to 15:14.000 --> 15:15.000 So I'd like to release that as a little library 15:15.000 --> 15:18.000 But the search engine itself is going along 15:19.000 --> 15:20.000 It's been brought online 15:21.000 --> 15:23.000 And a couple of people have given the URL out to 15:24.000 --> 15:25.000 Because they're going to test for some SQL injection 15:25.000 --> 15:26.000 To see if I missed anything 15:27.000 --> 15:29.000 But hopefully next week I'll be able to post in the forums 15:30.000 --> 15:31.000 The actual URL 15:32.000 --> 15:33.000 And we'll give everybody a chance to go in there 15:34.000 --> 15:35.000 And just see if they can't damage it 15:36.000 --> 15:37.000 So, it should be a lot of fun 15:38.000 --> 15:40.000 And I'm looking forward to finishing that project up 15:40.000 --> 15:42.000 It's been definitely a big learning experience 15:42.000 --> 15:44.000 And there's a huge difference in just 15:45.000 --> 15:47.000 When you really think about it, it sounds like it'd be easy 15:48.000 --> 15:51.000 Like, you know what, we'll just throw a bunch of words into a database and search through them 15:52.000 --> 15:53.000 But you have to consider so many other things 15:54.000 --> 15:58.000 Like you can't, normally what you would do if you're going to search through a whole bunch of text for a specific string 15:59.000 --> 16:01.000 In SQL queries, as long as we're talking about that 16:02.000 --> 16:04.000 Specifically for this implementation, I use Postgres 16:05.000 --> 16:06.000 I would have liked to have used Oracle 16:07.000 --> 16:09.000 But, you know, Oracle is expensive and I don't have that 16:09.000 --> 16:12.000 So anyway, normally what you would do is like a likes search 16:13.000 --> 16:15.000 And what that'll do is it'll, it slows anything 16:16.000 --> 16:18.000 And it searches the full text of everything as you're going through 16:19.000 --> 16:21.000 But it's criminally inefficient 16:22.000 --> 16:25.000 So what I'm using is what's called the t-search vectors 16:26.000 --> 16:30.000 And that is a plugin, it's in the contrib directory of the Postgres download 16:31.000 --> 16:33.000 If you download the full source code 16:33.000 --> 16:39.000 But, what's nice about the t-search is it actually stems and stops as it's going through 16:40.000 --> 16:41.000 What that means is, as you're indexing pages 16:42.000 --> 16:44.000 It takes out a's and the's and is 16:45.000 --> 16:47.000 And all those little words that would just make the query take longer 16:48.000 --> 16:51.000 And it stems, meaning if you have, hmm, what are two words? 16:52.000 --> 16:54.000 Well you know you have words that end in ing 16:55.000 --> 16:57.000 That can also end in ed, you know, suffixes, things like that 16:57.000 --> 17:02.000 They all get pulled off and so that you just have a cache of the actual word itself 17:03.000 --> 17:08.000 Now when you do an actual search, you can't just search this special created t-search 17:09.000 --> 17:10.000 Forum or table 17:11.000 --> 17:13.000 It's actually a column, a column in a table 17:14.000 --> 17:16.000 But you can't just search it with a normal like or anything 17:17.000 --> 17:18.000 You also have to use the t-search vectors again 17:19.000 --> 17:21.000 So we go ahead and that's tons of fun 17:22.000 --> 17:25.000 And, you know, the relevance isn't quite perfect, it needs to be tuned a lot more 17:25.000 --> 17:32.000 I think what I'm going to do is put more weight to the value of the text that's actually in the URL or in the title 17:33.000 --> 17:35.000 But I didn't really think about that in advance 17:36.000 --> 17:40.000 And that's why it's always important to make sure you have a really good design out for what you're going to do 17:41.000 --> 17:42.000 But I think that would really help relevance 17:43.000 --> 17:47.000 If anybody else has any good ideas, if anybody's ever, you know, researched or worked like that 17:48.000 --> 17:52.000 Because I'm not really a database programmer, I just like to mess around with everything, I guess 17:52.000 --> 17:56.000 It's a great way to learn everything that's out there, just to try new things 17:57.000 --> 17:59.000 So, that's what's going on with my search engine 18:00.000 --> 18:01.000 Hopefully soon we'll get that out 18:02.000 --> 18:03.000 And hopefully soon we'll get the rest of the crew back on 18:04.000 --> 18:05.000 Oh, is that what we hear them? 18:06.000 --> 18:07.000 Would that be Ratchet? 18:08.000 --> 18:10.000 Boy, the gremlins are out tonight 18:11.000 --> 18:14.000 Alright! Just as I ran out of stuff to say 18:15.000 --> 18:16.000 That's pretty good! 18:16.000 --> 18:17.000 Thank you, Zygmunt, for carrying the show like that 18:18.000 --> 18:19.000 You might have a future in radio 18:20.000 --> 18:21.000 That's what I could do 18:21.000 --> 18:23.000 I'm going to need a shot of liquor or something after all this 18:24.000 --> 18:25.000 Yeah, I know, tell me about it 18:26.000 --> 18:31.000 Well, we've moved on to the more reliable semi-cellphone landline 18:32.000 --> 18:33.000 So, shall we go into the email? 18:34.000 --> 18:35.000 Yeah, let me check to it 18:36.000 --> 18:37.000 Let me see if I can bridge that music in 18:38.000 --> 18:39.000 Hold on 18:39.000 --> 18:40.000 If not, we may just, you know 18:40.000 --> 18:43.000 Should we just start reading email and not tempt the gods at this point? 18:43.000 --> 18:44.000 Let's try it 18:44.000 --> 18:45.000 Try it 19:09.000 --> 19:11.000 Our first email is from Cypress 19:11.000 --> 19:12.000 And he says 19:12.000 --> 19:14.000 I was just sitting in school where my buddy installed Tor 19:15.000 --> 19:18.000 And I was wondering if it would be possible to run a massive man-in-the-middle attack on Tor 19:18.000 --> 19:19.000 Is that possible? 19:20.000 --> 19:24.000 Could you just run FragRouter and or similar programs and just collect user data and passwords using the SSL dump? 19:25.000 --> 19:26.000 Keep up the great work on the show, guys 19:27.000 --> 19:30.000 P.S. I'm the guy that emailed you before about the weird chemistry teacher and that you go 19:31.000 --> 19:32.000 Plus plus Cypress 19:34.000 --> 19:37.000 I actually wonder if it's plus plus Cypress or just pronounced Cypress or 19:38.000 --> 19:39.000 Double cross Cypress 19:39.000 --> 19:40.000 Double cross Cypress 19:40.000 --> 19:41.000 Yeah 19:41.000 --> 19:42.000 It actually sounds great 19:42.000 --> 19:43.000 Double plus or double cross? 19:43.000 --> 19:44.000 Yeah 19:44.000 --> 19:46.000 You answer the email, I'm getting some alcohol 19:47.000 --> 19:49.000 You know, sounds like a good plan to me 19:49.000 --> 19:50.000 That's what I should have done when I got my cell phone 19:50.000 --> 19:51.000 I was right in the kitchen 19:51.000 --> 19:52.000 Ah, what a well 19:53.000 --> 19:56.000 Anyway, I actually was thinking about this for a while 19:56.000 --> 19:59.000 And then I decided, hey, let's go actually consult the TorFact 20:00.000 --> 20:02.000 And the TorFact states 20:03.000 --> 20:06.000 Every Tor server has a public decryption key rotated once a week 20:07.000 --> 20:12.000 When Tor clients establish circuits at each step, they demand the Tor server prove knowledge of its private key 20:13.000 --> 20:16.000 That way the first no in the path can't just move the rest of the path 20:17.000 --> 20:21.000 How do clients know what the servers are and how do they know that they have the right keys for them? 20:21.000 --> 20:31.000 The directory servers provide a signed list of all the approved servers and that lists are set as a set of self-signed certificates from each servers 20:32.000 --> 20:35.000 Specifying their keys, locations, exit policies and so on 20:35.000 --> 20:42.000 So unless the adversary can control a directory server and starting in Tor 011x 20:43.000 --> 20:45.000 A threshold of directory servers 20:46.000 --> 20:49.000 He can't trick the Tor client into using other Tor servers 20:50.000 --> 20:52.000 How do clients know what directory servers are? 20:53.000 --> 20:56.000 The list comes with Tor distribution and hardcodes their locations and their public keys 20:57.000 --> 21:03.000 So the only way to trick the user into using a fake Tor network is to give them a specially modified version of the software 21:03.000 --> 21:08.000 So, double-crossed Zypress or whatever your name is, it's about a possible 21:09.000 --> 21:14.000 I would assume that the EFS is kind of sticky on this whole privacy issue thing 21:15.000 --> 21:18.000 So they probably have some of the best and the brightest people working on it 21:19.000 --> 21:23.000 So I would think it would be kind of secure, but you know, who knows 21:24.000 --> 21:28.000 The Tor's only real competition to security is against a global adversary 21:28.000 --> 21:29.000 Yes 21:29.000 --> 21:34.000 And that is an adversary who has large control or the ability to sniff large parts of the network 21:35.000 --> 21:40.000 Because if they can see you going into a traffic node and they can also see traffic coming out from another node 21:41.000 --> 21:44.000 They can't prove that it was you, but if they happen to see a large enough part of the network 21:44.000 --> 21:49.000 And it just so happens that every time something comes in from you, something happens to go out from somewhere else 21:49.000 --> 21:52.000 And they can correlate to times, they can actually sniff your traffic 21:53.000 --> 21:54.000 Because it's going to come out unencrypted 21:55.000 --> 21:58.000 Unless, of course, there's some sort of encryption going on, like you're using SSH or SSL 21:59.000 --> 22:02.000 But Tor has been a pretty damn good product 22:03.000 --> 22:04.000 Especially since it's free 22:04.000 --> 22:06.000 It's free 22:07.000 --> 22:08.000 Free 22:09.000 --> 22:10.000 Yeah, Tor is good 22:11.000 --> 22:13.000 I would think that it would be kind of secure 22:14.000 --> 22:15.000 And they'd probably take into attacks like this 22:16.000 --> 22:19.000 But I think we had an episode on Tor that Zigma was on, now that I think of it 22:20.000 --> 22:21.000 We did 22:21.000 --> 22:22.000 So, I mean, we talked about it there 22:22.000 --> 22:25.000 And if you also want to look at last week's episode 22:26.000 --> 22:30.000 We talked about SSH and public versus private Cree encryption 22:31.000 --> 22:37.000 And that gives you a, it gives you a, sort of a hint of what they're up against 22:38.000 --> 22:41.000 So, either way, yeah 22:42.000 --> 22:43.000 You know, Tor is secure 22:44.000 --> 22:45.000 Well, I wouldn't say Tor is not completely secure 22:46.000 --> 22:49.000 When you start it up, it tells you right there, do not use your strong anonymity 22:49.000 --> 22:53.000 But, you know, I think you're pretty good for normal web browsing 22:56.000 --> 22:57.000 Oh, next email 22:58.000 --> 23:00.000 Alright, our next email, now that I've got some rum in me 23:01.000 --> 23:03.000 Hey, Strom and Black Ratchet 23:04.000 --> 23:06.000 You mentioned polyphasic sleep at the beginning of your show 23:07.000 --> 23:08.000 Actually, this is at the beginning of your show, but whatever 23:09.000 --> 23:11.000 I would not recommend that any of your listeners actually try this 23:12.000 --> 23:14.000 As a way of getting more time in the day off for hacking 23:14.000 --> 23:17.000 It's true that people who are sleep deprived either REM fairly quickly 23:18.000 --> 23:19.000 Or enter REM fairly quickly 23:20.000 --> 23:22.000 However, REM is not the only important phase of sleep 23:23.000 --> 23:26.000 For example, REM is not the only stage of sleep associated with dreaming 23:27.000 --> 23:30.000 And dreaming in all stages of sleep has been found to be extremely important for learning and memory 23:31.000 --> 23:35.000 If you do want to hack your sleep, you might want to try using it to improve your ability to learn new tasks 23:35.000 --> 23:41.000 For example, if you're working on some code and come to a bug that seems unfixable, try taking a nap and then coming back to it 23:42.000 --> 23:45.000 While you're asleep, your brain might come up with a solution you never thought you could think of 23:46.000 --> 23:50.000 The brain is funny like that, works the same for playing video games, doing logic puzzles, studying for tests, etc. 23:51.000 --> 23:52.000 Peace, Mystic 23:52.000 --> 23:53.000 Mystic 23:55.000 --> 23:56.000 Well, Mystic, thanks for your 23:57.000 --> 24:00.000 I'm curious if you actually, whether or not you've actually done polyphasic sleep 24:01.000 --> 24:05.000 And I'm curious as to whether or not we actually have someone who listens and does or has done 24:06.000 --> 24:12.000 Or actually has some experience with polyphasic sleep and what their take on it was as it were 24:13.000 --> 24:16.000 But interesting observation, I wasn't actually completely aware of that 24:16.000 --> 24:24.000 Personally, with your whole and your second thing, you know, going away and taking a nap while trying to munch in a large problem 24:25.000 --> 24:29.000 My experience is that if I walk away from a tough problem, you know, whether I sleep or not 24:30.000 --> 24:35.000 And when I come back to tackle it again, you know, a new solution that I hadn't really thought of usually presents itself 24:36.000 --> 24:44.000 Not all the time, of course, but I think it's less of a matter, at least for me, it could be, you know, different, you know, folks could have different things 24:44.000 --> 24:50.000 But for me, I guess it's less of a matter of taking a rest from the constant non-stop thinking about the problem 24:51.000 --> 24:54.000 Rather than actually just, like, taking a nap 24:55.000 --> 25:02.000 Like, my case in point, I mean, today, you know, for those who don't know, I'm usually on, you know, IRC Monday through Friday 9 to 5 25:03.000 --> 25:07.000 I'm not always on there, but I'm usually logged in and I'm, you know, reading the mail at least 25:07.000 --> 25:14.000 I mean, if you're on there from 9 to 5, you'll often see me, you know, pop in for a bit and then suddenly leave for like a large extended period of time 25:14.000 --> 25:18.000 And, you know, 9 times out of 10, the reason behind this is, you know, I'm taking a break 25:19.000 --> 25:21.000 I'm trying to, you know, stop thinking about the problem 25:22.000 --> 25:25.000 Whatever I'm chewing on at the moment, and then I come back to tackle it 25:25.000 --> 25:27.000 And it usually works 25:28.000 --> 25:32.000 Since we're on the, talking about hacking your sleep and all that stuff 25:33.000 --> 25:37.000 I'm curious that the old stories of, you know, listening to stuff while you sleep 25:38.000 --> 25:42.000 You know, listening to Spanish while you sleep and you'll learn Spanish while you're taking a nap 25:43.000 --> 25:47.000 Are actually true, and I'm actually curious if any listeners have experience with that 25:47.000 --> 25:48.000 See, what's up with you again? 25:48.000 --> 25:49.000 See, what's up with you again? 25:50.000 --> 25:51.000 Hmm? 25:52.000 --> 25:56.000 See, he was speaking Spanish when he learned through, uh, through his sleep learning 25:56.000 --> 25:58.000 I think I just said yes, it uses very well 25:59.000 --> 26:01.000 So, obviously, my Spanish is off 26:02.000 --> 26:06.000 Oh, I don't know, I'm on GSM, so it all sounds horrible 26:07.000 --> 26:09.000 Yeah, it sounds horrible on this end, too, anyway 26:10.000 --> 26:13.000 Well, the whole polyphasic thing, you know, the whole polyphasic sleep 26:13.000 --> 26:17.000 Of course, you should never actually, like, do anything that we talk about on the radio show 26:18.000 --> 26:20.000 Because it's really just something that we all kind of get together and do for fun 26:21.000 --> 26:25.000 So, of course, never, you know, I guess, insert disclaimer, you know, speak with your doctor 26:26.000 --> 26:29.000 But, um, I have heard a lot of mixed reviews on the whole polyphasic sleep subject 26:30.000 --> 26:32.000 And one site that has a lot of really good information about it 26:33.000 --> 26:36.000 It's a blog from somebody who actually has successfully made his transition 26:37.000 --> 26:41.000 And he talks about where he had trouble and why he thinks it's better and why he thinks it's not as good 26:41.000 --> 26:45.000 And it doesn't only have his point of view, it has the point of view of his wife as well 26:46.000 --> 26:48.000 And how it's like to live with somebody who's changed their sleep style 26:49.000 --> 26:50.000 The guy's name is, uh, Steve 26:51.000 --> 26:52.000 And I'm going to butcher the last name 26:53.000 --> 26:54.000 It's Pavlina 26:55.000 --> 26:56.000 P-A-V-L-I-N-A 26:57.000 --> 26:58.000 Please accept my apologies for checking it up 26:59.000 --> 27:00.000 Steve Pavlina 27:00.000 --> 27:01.000 I tiny URL'd it 27:01.000 --> 27:02.000 It's tinyurl.com 27:03.000 --> 27:06.000 Slash A-A-L-X-K 27:07.000 --> 27:08.000 Whatever that is in fancy talk 27:09.000 --> 27:10.000 But, uh, 27:11.000 --> 27:12.000 Oh, 27:13.000 --> 27:14.000 Kilowatt 27:15.000 --> 27:16.000 But, uh, it's just something, if you are seriously considering it 27:17.000 --> 27:19.000 You should check out that blog and I'll tell you more about it 27:20.000 --> 27:22.000 So, if somebody wants to be seriously 27:23.000 --> 27:24.000 Go ahead 27:24.000 --> 27:28.000 Go ahead 27:29.000 --> 27:30.000 Go ahead, Zygmunt 27:31.000 --> 27:32.000 Oh, I'm done. Go ahead. I'm sorry 27:33.000 --> 27:35.000 Well, I think Zygmunt actually brought up a very important point 27:36.000 --> 27:38.000 Actually, not never to take the show seriously 27:39.000 --> 27:40.000 And we don't know what the hell we're doing 27:41.000 --> 27:42.000 Yes, ever 27:43.000 --> 27:44.000 Entertainment purposes only 27:45.000 --> 27:47.000 If you ever think you know what we're doing 27:48.000 --> 27:49.000 Or you think we know what we're doing 27:50.000 --> 27:51.000 Pop on the IRC 27:51.000 --> 27:52.000 Talked to a good man 27:53.000 --> 27:54.000 His name is P. Oxby 27:55.000 --> 27:56.000 And asked him what he thinks of the show 27:57.000 --> 27:59.000 So, I mean, he, he, earlier in the IRC 28:00.000 --> 28:02.000 He was, uh, saying that we had a content-ectomy, so 28:03.000 --> 28:04.000 A content what? A content-ectomy? 28:05.000 --> 28:06.000 Yeah, a content-ectomy 28:07.000 --> 28:09.000 But he always complains about our, our apparent lack of content 28:10.000 --> 28:11.000 Yeah 28:12.000 --> 28:13.000 Well, we had some technical difficulties today 28:14.000 --> 28:15.000 So I think that's to be excusable 28:16.000 --> 28:17.000 And we haven't even gotten to the good stuff 28:17.000 --> 28:18.000 Yeah, it was actually before our shoes 28:18.000 --> 28:19.000 So, he's probably like, you know 28:19.000 --> 28:21.000 He probably ran off when I dropped 28:22.000 --> 28:25.000 Anyway, uh, who's our next email from? Magnum IP? 28:26.000 --> 28:28.000 Our next email is, yeah, from Magnum IP 28:29.000 --> 28:31.000 And, uh, let's see, he says 28:32.000 --> 28:36.000 Oh, before we go on, I should probably say that, like, this past week or two 28:37.000 --> 28:39.000 I've been not sleeping, I've been sleeping kind of a few hours in the afternoon 28:40.000 --> 28:41.000 A few hours during the day 28:41.000 --> 28:42.000 It sucks 28:43.000 --> 28:44.000 Major balls 28:46.000 --> 28:47.000 I, I prefer 28:48.000 --> 28:49.000 Yeah, I, I prefer my solid eight hours 28:50.000 --> 28:51.000 From sleeping method 28:52.000 --> 28:53.000 Yeah 28:54.000 --> 28:55.000 So, anyway, Magnum IP writes 28:56.000 --> 29:00.000 Hey guys, I called in on one of your live shows when you were asking people to call in and talk about pretty much anything 29:01.000 --> 29:06.000 I ranted about how the new WRT 54G dot, er, V.5 VX works firmware is horrendous 29:07.000 --> 29:11.000 I also ranted on Verizon installing Fios in my whole neighborhood but my street 29:12.000 --> 29:17.000 Well, after numerous calls to the main office, they admitted to a computer area stating it was reported that the cables were already laid 29:17.000 --> 29:20.000 And everything was ready for Fios service on my street when in fact it wasn't 29:21.000 --> 29:23.000 Verizon is sending engineers out to start the work in a week or two 29:24.000 --> 29:29.000 Can't wait to get my asterisk box finally installed and working with 15 megabit down and 2 megabit up, damn you 29:30.000 --> 29:33.000 I also have a gripe about a certain ISP in my area about their policies on password retrieval 29:34.000 --> 29:39.000 My friend forgot her password to her new email address from her new DSL account she got from a local telco 29:40.000 --> 29:42.000 She never used it because she's still using AOL for her email 29:42.000 --> 29:47.000 Well, as an experiment, I emailed the ISP asking for my password from her AOL email address 29:48.000 --> 29:51.000 After about two days, I sent the password in a reply without confirming any information 29:52.000 --> 29:55.000 Or asking to call the 800 number to talk to a live operator to verify information 29:56.000 --> 29:59.000 In my mind, that's a very big no-no, shame on this local telco 30:00.000 --> 30:01.000 Thanks for your time, Magnum IP 30:02.000 --> 30:05.000 P.S. Strom is my secret love monkey 30:06.000 --> 30:07.000 Strom, I had no idea 30:08.000 --> 30:09.000 Yeah, neither did I 30:09.000 --> 30:12.000 I must do it while you're sleeping for those three hours a day 30:13.000 --> 30:14.000 Yeah, exactly 30:15.000 --> 30:18.000 Well, first off, congratulations on getting your Fiber to the premises 30:19.000 --> 30:24.000 I refuse to call it their little, whatever they call it Fios 30:25.000 --> 30:27.000 Did any of it actually stand for anything? 30:28.000 --> 30:30.000 It's probably like Fiber over or something, I don't know 30:31.000 --> 30:33.000 I don't know yet, I'll look 30:33.000 --> 30:35.000 You know, anyway 30:36.000 --> 30:42.000 I'll get Fiber to the premises from Verizon whenever they remove their asinine filtering policies 30:43.000 --> 30:46.000 And allow me to get a static IP address 30:47.000 --> 30:49.000 Without giving them my firstborn son 30:50.000 --> 30:53.000 Fios, according to Wikipedia, stands for Fiber Optic Services 30:53.000 --> 30:55.000 Trixie Hobbuses 30:56.000 --> 30:57.000 Trixie Hobbuses 31:00.000 --> 31:01.000 Hell yeah, now we all know 31:02.000 --> 31:04.000 I'm currently using their DSL now 31:05.000 --> 31:10.000 And I'm going to, it's going to, I think the contract is going to expire next January 31:11.000 --> 31:13.000 And I'm going to jump-sip the day after it goes out 31:13.000 --> 31:19.000 I already have like two or three ISPs lined up and me going to call them immediately afterwards 31:20.000 --> 31:22.000 And saying, set it up, do it now 31:23.000 --> 31:27.000 Yeah, I've got six megabit DSL here in California from a company called DSL Extreme 31:28.000 --> 31:30.000 Love them, no restrictions, no filtering whatsoever 31:31.000 --> 31:32.000 Cheap too 31:32.000 --> 31:36.000 Apparently, like, COVID doesn't have my CO 31:37.000 --> 31:39.000 So I'm like, like, what the, it sucks 31:40.000 --> 31:44.000 There's a, there's a small, it looks like there's a small mom and pop on Cape Cod 31:45.000 --> 31:48.000 Which is a, for those of you unfamiliar with Massachusetts, Cape Cod 31:49.000 --> 31:54.000 If you've ever seen a picture of Massachusetts, it's that little hook that sort of goes out onto the eastern part of the state 31:55.000 --> 31:56.000 It's Massachusetts Wang 31:57.000 --> 31:58.000 Yeah 31:58.000 --> 32:01.000 They can't have Florida, that's United States Wang 32:02.000 --> 32:03.000 Or America's Wang, whatever they call it 32:04.000 --> 32:08.000 But anyway, like, you know, there's a small mom and pop ISP called, like, Cape Cod.net 32:09.000 --> 32:12.000 And they actually have rather good service and reasonable prices 32:13.000 --> 32:14.000 So I think I'm going to have to hop over to them 32:15.000 --> 32:17.000 If, uh, Speakeasy or Kovad 32:18.000 --> 32:19.000 Or, it's Kovad who does Speakeasy 32:20.000 --> 32:21.000 And I think they also do their DSL Extreme 32:22.000 --> 32:26.000 Doesn't start on my, uh, CO 32:26.000 --> 32:30.000 So, personally, I just, I can't, in having a filter in place 32:31.000 --> 32:32.000 I, I had Speakeasy before, it was wonderful 32:33.000 --> 32:35.000 They gave me, like, you know, you know, killer speeds 32:36.000 --> 32:38.000 Their, their, their customer support was very cluel 32:39.000 --> 32:41.000 And I have literally, like, little to no complaints about them 32:42.000 --> 32:43.000 Like, maybe, maybe one 32:44.000 --> 32:45.000 But, other than that, it was absolutely fine 32:46.000 --> 32:51.000 Um, so, I, I just can't, I, I've experienced the Rolls-Royce 32:51.000 --> 32:53.000 I've refused to go back to the Pinto 32:54.000 --> 32:59.000 Um, personally, uh, your, your statement of a very big no-no 33:00.000 --> 33:02.000 Is, um, a very, is the understatement of the century 33:03.000 --> 33:04.000 Regarding the password policy 33:05.000 --> 33:06.000 I'm kind of disappointed that you didn't kind of 33:07.000 --> 33:09.000 Drop the name of the ISP 33:10.000 --> 33:13.000 So, you know, people that are looking for ISPs in your areas 33:13.000 --> 33:14.000 Will, can stay the hell away from it 33:15.000 --> 33:19.000 Um, although, I guess, if they kind of handed out passwords 33:20.000 --> 33:22.000 That would be, uh, a smart thing not to drop their name 33:23.000 --> 33:24.000 Because everyone would be like, oh, I need my password 33:25.000 --> 33:27.000 Well, everyone could just jump ship immediately, so 33:28.000 --> 33:31.000 Well, no, because, no, no, well, I mean, all the smart people would 33:32.000 --> 33:35.000 If they actually got out there, but none of the regular people would 33:36.000 --> 33:37.000 Yeah 33:38.000 --> 33:41.000 Um, in my opinion, you really need to contact someone about that 33:41.000 --> 33:45.000 That's, like, you know, very, very dangerous and very, very stupid 33:46.000 --> 33:50.000 Um, you know, find, like, find your ISP security officer 33:51.000 --> 33:54.000 If it's a small ISP, of course, you also used to term ELCO 33:55.000 --> 33:58.000 So, that's a bit annoying, um, it could be actually a telephone company 33:59.000 --> 34:00.000 Which, at which point, you're screwed 34:01.000 --> 34:03.000 Um, at that point, you may want to talk to your local newspaper 34:04.000 --> 34:08.000 Um, that really is a security breach waiting to happen 34:08.000 --> 34:15.000 So, yes, contact somebody, you know, find an adult 34:16.000 --> 34:19.000 Go tell them, at which point, afterwards, when they look at you funny 34:20.000 --> 34:22.000 You know, find the security officer, or find the local outlet 34:27.000 --> 34:32.000 So, yeah, that's about it, you know, just, you need, this issue needs to address 34:32.000 --> 34:35.000 We shouldn't be sending, you shouldn't be sending passwords over the email no matter what 34:35.000 --> 34:38.000 I mean, even, even if you have to verify who it is 34:39.000 --> 34:42.000 I mean, I'm, I'm never a fan of sending out passwords in plain text over emails 34:43.000 --> 34:45.000 So, fix it, this is your job 34:46.000 --> 34:47.000 Go do it, we want a full report 34:48.000 --> 34:51.000 Go take your 15 megabit bandwidth and go do something useful with it 34:51.000 --> 34:54.000 Alright 34:55.000 --> 34:57.000 Um, our next email is from Teoxy 34:58.000 --> 34:59.000 Is it? 35:00.000 --> 35:01.000 Amazing, yes he is 35:02.000 --> 35:03.000 Ah, okay 35:04.000 --> 35:06.000 I actually think he uses his name, but we're not going to actually, we're just going to actually point out, fact out 35:07.000 --> 35:08.000 That he emailed the show 35:09.000 --> 35:10.000 Gas 35:10.000 --> 35:12.000 No wonder we're having technical difficulties tonight 35:13.000 --> 35:14.000 Hell is freezing over 35:15.000 --> 35:16.000 Yeah, amazing 35:17.000 --> 35:18.000 Anyway 35:21.000 --> 35:22.000 The email is, oh, yeah 35:23.000 --> 35:24.000 That's the liquor talking 35:25.000 --> 35:27.000 The book you're thinking of is Firewalls and Internet 35:27.000 --> 35:29.000 Or sorry, the book you're thinking of, Firewalls and Internet 35:30.000 --> 35:31.000 He left as an is 35:32.000 --> 35:35.000 The book you're thinking of is Firewalls and Internet Security by Cheswick and Belevin 35:36.000 --> 35:39.000 The story was a paper Belevin published and isn't the only free material in the book 35:40.000 --> 35:43.000 There's also the paper, There Be Dragons, which discusses a related topic 35:44.000 --> 35:48.000 The paper is available at tinyurl.com slash RomeoLimaMikeEcho4 35:49.000 --> 35:50.000 I also had a question about 35:51.000 --> 35:52.000 What? 35:53.000 --> 35:54.000 What? 35:55.000 --> 35:56.000 Very good, you actually get all right, amazing 35:57.000 --> 35:58.000 Yeah, I'm learning my alphabets 36:01.000 --> 36:02.000 LOL Internet 36:02.000 --> 36:04.000 I also had a question about user mode Linux 36:05.000 --> 36:06.000 If you use raw sockets in user mode Linux 36:07.000 --> 36:08.000 How is that implemented if you aren't running as root? 36:09.000 --> 36:12.000 Can't you use that facility to determine with fair likelihood if you're in UML? 36:15.000 --> 36:16.000 You know, I've done some socket programming 36:17.000 --> 36:20.000 And, you know, if you're not root and you try to open a raw socket 36:21.000 --> 36:22.000 I'm pretty sure you get an error 36:23.000 --> 36:26.000 And the error you get is error, proto, no support 36:27.000 --> 36:28.000 Which is the protocol not supported 36:28.000 --> 36:31.000 And I, you know, I could totally be wrong about this 36:32.000 --> 36:37.000 But I'm pretty sure that that's also the reason why if you try to run nmap and you do certain tests when you're not root 36:38.000 --> 36:41.000 It'll tell you you can't run that test unless you're a super user 36:42.000 --> 36:46.000 And I, that's not something I'm 100% wrong, so don't take that to the bank 36:46.000 --> 36:49.000 But I'm pretty sure that if you try to open that socket as root 36:50.000 --> 36:53.000 Any raw socket as root, you're going to get that error, no prot support error 36:56.000 --> 36:59.000 I actually submitted this question to a couple people that I know 36:59.000 --> 37:00.000 And they were all scratching their heads 37:01.000 --> 37:03.000 So at this point, I am not going to be able to answer this 37:03.000 --> 37:04.000 However, I will get an answer 37:04.000 --> 37:08.000 Teoxi was very kind and actually milled us last week 37:09.000 --> 37:13.000 However, he had the unfortunate mishap of being between two pieces of spam 37:14.000 --> 37:18.000 So, you know, he sort of bled it into the background 37:19.000 --> 37:23.000 But, I need to do some research into this 37:24.000 --> 37:26.000 And I actually want to try this, because this is a very good question 37:27.000 --> 37:31.000 However, if someone actually doesn't know the answer, just feel free to email us at radio at binrub.com 37:31.000 --> 37:35.000 So, congratulations Teoxi, you have stumped BIM Rev Radio 37:36.000 --> 37:38.000 I'm sure you're very giddy about this, and we'll put it on your resume 37:39.000 --> 37:42.000 We should send him a trophy, you've stumped BIM Rev Radio 37:43.000 --> 37:46.000 We'd have to be giving out a lot of trophies 37:47.000 --> 37:48.000 Yeah, I know, tell me about it 37:50.000 --> 37:52.000 Everybody's got us beat on something 37:53.000 --> 37:54.000 Yeah 37:56.000 --> 37:59.000 All right, let's go in the show and tell 37:59.000 --> 38:01.000 Dr. Zygmunt, what have you been working on this week? 38:01.000 --> 38:04.000 You know, I think I believe I've already told this story 38:05.000 --> 38:06.000 Yeah, he's 38:06.000 --> 38:07.000 While you were MIA 38:08.000 --> 38:12.000 Yeah, he pulled it out of nowhere and used wonderful filler while we tried to get you back on the 38:13.000 --> 38:16.000 I earned my mutant ability of the filibuster 38:18.000 --> 38:20.000 The Democrats will want you 38:20.000 --> 38:22.000 I could go run for Senate 38:23.000 --> 38:28.000 Well, what have you been doing then, if Dr. Zygmunt's already blown his load 38:29.000 --> 38:31.000 What have I been doing? Jeez, um 38:35.000 --> 38:40.000 Apart from battling with Asterisk and my machine 38:41.000 --> 38:44.000 That was only like 15 minutes, so what else did you do this week? 38:45.000 --> 38:47.000 Um, nothing major to speak of, I think 38:48.000 --> 38:50.000 Just, uh, yeah 38:53.000 --> 38:54.000 Fun in the sun 38:55.000 --> 38:58.000 Yeah, fun in, well, it should be sun here in Southern California, but it's not 38:59.000 --> 39:02.000 It's rain and rain and more miserable rain 39:02.000 --> 39:05.000 Aw, poor straw 39:06.000 --> 39:09.000 He's scared of his little rain, he doesn't like the cloudiness 39:10.000 --> 39:11.000 Oh, I'm not scared of it, it's just 39:12.000 --> 39:13.000 It made my commute home today 39:14.000 --> 39:15.000 Two hours 39:16.000 --> 39:17.000 Yeah 39:18.000 --> 39:24.000 Personally, you know, at least in Boston when it rains, the commute's always two hours 39:25.000 --> 39:26.000 So, hey, what have I been doing? 39:27.000 --> 39:30.000 Um, what have I been doing? 39:31.000 --> 39:35.000 Let's see, I, I have been, um, I've been data mining for, for work 39:36.000 --> 39:40.000 And you've actually, if you've been an IRC, you can hear me complain about this, uh, software that I've been trying to use 39:41.000 --> 39:47.000 Basically, we've had this software sitting around, um, this highly expensive piece of software 39:48.000 --> 39:51.000 The software quite literally cost about $10,000 39:51.000 --> 39:58.000 Um, and, it's used to data mine two separate databases, and I'm doing this for work 39:59.000 --> 40:03.000 And it's, it's nothing, you know, gray area, illegal, slightly immoral, it's completely fine 40:04.000 --> 40:09.000 It's basically, we're looking at dead people, so, it's a matter of public record and all that wonderful stuff 40:10.000 --> 40:12.000 Either way, I've been seeing dead people 40:13.000 --> 40:16.000 I've been seeing dead people all week, last week as well 40:16.000 --> 40:21.000 So, the, the software package, we'll, we'll just sort of, it's, it's actually owned by IBM now 40:22.000 --> 40:25.000 It's gone through, like, two or three different people, two or three different, uh, company ownerships 40:26.000 --> 40:28.000 So, we've got, it's called, um, Integrity Designer 40:29.000 --> 40:31.000 And, it sucks, don't use it 40:32.000 --> 40:35.000 Of course, no one will actually use it, because it costs $10,000 freaking dollars 40:35.000 --> 40:42.000 And, after banging my head against the software for, oh, I'd say about a week 40:43.000 --> 40:46.000 I finally sat down, and I wrote a bunch of Perl scripts out 40:47.000 --> 40:49.000 That basically replicated exactly what it did 40:50.000 --> 40:54.000 And, I think the only slight advantage that it has is that it's slightly faster 40:55.000 --> 40:58.000 And, I think if I probably actually sat down, worked out some threading into these Perl scripts 40:59.000 --> 41:02.000 It would, I, it would give it a very good run for its money 41:02.000 --> 41:06.000 But, you know, the software to which we've paid, you know, $10,000 to initially buy 41:07.000 --> 41:10.000 And then a, like, you know, three or four year, uh, service contract 41:11.000 --> 41:16.000 That my predecessor recommended at work, um, for, like, $5,000 a year 41:17.000 --> 41:20.000 We, we, we, we've, we've clocked down, like, you know, a good chunk of change about this 41:21.000 --> 41:26.000 And I, I, I've written in about a week, software that basically emulates a good majority of its functions 41:27.000 --> 41:29.000 And, I actually feel kind of proud about that 41:29.000 --> 41:31.000 They should've just given you the $10,000 41:32.000 --> 41:33.000 God, that would be great 41:34.000 --> 41:35.000 That'll be the day 41:36.000 --> 41:37.000 No, it doesn't work that, it doesn't work like that 41:38.000 --> 41:39.000 Hell no 41:40.000 --> 41:44.000 Um, but yeah, that's, that's what I've been doing 41:45.000 --> 41:46.000 And I'm sick and tired of looking at statistics 41:47.000 --> 41:50.000 And I, I, I think I, I set up for a nice little, you know, batch run tonight 41:51.000 --> 41:54.000 And hopefully when I, I stroll in tomorrow morning, I'll be able to wash my hands of 41:54.000 --> 41:56.000 It's gonna fail on the first query 41:57.000 --> 42:01.000 No, no, no, no, no, I actually did a couple of dry runs on it, so I know it was at least working 42:01.000 --> 42:02.000 Okay, okay 42:02.000 --> 42:05.000 We're knock on wood right now, because you brought it up, you, you, you horrible 42:06.000 --> 42:08.000 You know what's, you know what's really surprising? You know what's going on? 42:09.000 --> 42:12.000 People are logging into the IRC channel to tell us things 42:12.000 --> 42:17.000 Well, let's say that, people have done that before 42:17.000 --> 42:19.000 Yeah, but like, surprisingly a lot tonight 42:20.000 --> 42:23.000 So, just to answer you guys, yes, we know we're having technical difficulties 42:24.000 --> 42:26.000 And we know there's echo, please stop telling us 42:27.000 --> 42:29.000 But we do appreciate you telling us 42:29.000 --> 42:31.000 Yes, we do appreciate you pointing it out initially, but 42:32.000 --> 42:35.000 Now that we're totally aware of it, uh, thanks, we know 42:35.000 --> 42:43.000 And, uh, to Eggman, who logged in to tell, to say, uh, tell Strom to quit bitching about the rain 42:43.000 --> 42:45.000 It's been raining for 38 days here 42:46.000 --> 42:47.000 I totally sympathize with you 42:48.000 --> 42:51.000 But still, Jesus Christ, rain, no 42:52.000 --> 42:56.000 And actually, it's not me echoing, I believe it's actually Dr. Zegman, but we'll get into that 42:56.000 --> 42:58.000 Because it was echoing before he got on the cell phone 42:59.000 --> 43:00.000 Yeah 43:01.000 --> 43:02.000 I don't know 43:02.000 --> 43:03.000 No, no, no, no 43:04.000 --> 43:05.000 Whatever, who cares 43:05.000 --> 43:07.000 We'll run some digital, technical jiggle 43:07.000 --> 43:09.000 We'll only poke through you over it later 43:09.000 --> 43:12.000 In the archives, so no one ever will be listening to the archives going, I don't hear an echo 43:13.000 --> 43:14.000 God, anyway 43:14.000 --> 43:15.000 I hope I can do that 43:16.000 --> 43:17.000 Shush 43:17.000 --> 43:18.000 Actually, the echo's worse now 43:18.000 --> 43:21.000 Can you, can you drop, Zegman, I'll call you again 43:22.000 --> 43:23.000 Okay 43:25.000 --> 43:26.000 Okay, check 43:27.000 --> 43:28.000 Yeah, it was him, okay 43:29.000 --> 43:30.000 Aha 43:30.000 --> 43:31.000 All these horrible people 43:31.000 --> 43:32.000 Anyway 43:33.000 --> 43:35.000 Our topic tonight is 43:36.000 --> 43:37.000 Bioinformatics 43:38.000 --> 43:39.000 Actually, I think it's bioinformatics 43:39.000 --> 43:40.000 That's how I pronounce it 43:40.000 --> 43:41.000 It could be bioinformatics for all I know 43:42.000 --> 43:45.000 And actually, the reason why we have Zegman on the show tonight 43:45.000 --> 43:48.000 Is because this is what Zegman actually goes to school for 43:49.000 --> 43:50.000 Which is amazing 43:50.000 --> 43:52.000 And it's actually kind of inconvenient because he's not here right now 43:52.000 --> 43:56.000 But, what bioinformatics is 43:57.000 --> 44:01.000 Basically, bioinformatics is a, it's computational biology 44:02.000 --> 44:09.000 And what it does, it involves the use of, you know, applied mathematics, informatics, statistics, and computer science 44:09.000 --> 44:15.000 And they all, you know, tie them together with chewing gum and tape and all that wonderful stuff 44:16.000 --> 44:19.000 And they use it to solve biological problems 44:20.000 --> 44:29.000 Like, we'll go into like what this actual biological problem is because Zegman can actually speak for this a lot better than I can with the actual applications uses 44:29.000 --> 44:39.000 I've just been, I've been kind of fooling around with it because that's actually one of the applications that this data-minded compassion that I have has used for 44:40.000 --> 44:41.000 It's what they kind of pimp it out as 44:42.000 --> 44:47.000 But we won't actually, I don't touch it and I have no clue about it and it won't actually do it 44:48.000 --> 44:53.000 But, computational biology research often overlaps with, you know, systems biology 44:53.000 --> 45:01.000 Major effort, major efforts in the field of, you know, gene sequencing alignments, gene findings, genome essentially 45:02.000 --> 45:08.000 For those of you who don't remember, you know, back in 2000, the genome project where they mapped an entire 45:09.000 --> 45:12.000 Zegman, what is actually the map? They mapped a 45:13.000 --> 45:19.000 The Human Genome Project, where they actually sequenced, they didn't map, but they sequenced the entire genome 45:19.000 --> 45:22.000 They're still sequencing it now, or I'm sorry, they're still mapping it now 45:22.000 --> 45:30.000 And by mapping we mean being able to identify this sequence is for this gene, this sequence is for this gene, and so on and so forth 45:31.000 --> 45:36.000 Okay, so basically I've told everyone that, is it bioinformatics or informatics? 45:37.000 --> 45:39.000 I think that's tomato, tomato 45:39.000 --> 45:40.000 Okay 45:40.000 --> 45:41.000 Well you wrote 45:41.000 --> 45:42.000 I like, in general sounds cool 45:42.000 --> 45:43.000 Who wrote this up wrote definition 45:45.000 --> 45:46.000 Huh? 45:46.000 --> 45:49.000 Whoever wrote this up wrote web definition instead of web definition, so 45:49.000 --> 45:52.000 Hey, okay, yeah, well that's why I'm a biology major 45:53.000 --> 45:56.000 And I'm a social science major, so 45:57.000 --> 46:03.000 Go, go, go, go, go step off to the side there and, you know, go, go hear your spelling Nazi in silence 46:03.000 --> 46:04.000 Boots 46:04.000 --> 46:05.000 Yes 46:06.000 --> 46:10.000 So, okay, you can probably explain, like I was telling everyone, this is what you go for school for, right? 46:11.000 --> 46:17.000 Well, I'm a biology, well I'm actually a triple major, which is biology, computer science, and chemistry 46:18.000 --> 46:22.000 But I do plan to be a doctor, and bioinformatics is something that I was definitely looking in 46:22.000 --> 46:29.000 Because it combines not only excellent job opportunities for somebody who is thinking, maybe what do I want to do with my life 46:30.000 --> 46:35.000 But it also allows you to really do work that's going to make a big difference in people's lives 46:36.000 --> 46:43.000 And really, bioinformatics is becoming such a huge field that daily, we'll talk about some of the databases later 46:44.000 --> 46:51.000 But researchers are using these to save thousands and thousands of hours of sequencing things themselves in the lab 46:51.000 --> 46:58.000 And it's really, just the sheer amount of data that's involved is requiring such advanced programming 46:59.000 --> 47:07.000 That anybody who really wants to take a leap and get into this sort of work can have a really good job for a really long time 47:08.000 --> 47:14.000 And I'm not sure exactly what we said so far, but if you want to start the ball rolling, we'll go from there 47:14.000 --> 47:21.000 I mean, I just talked about what it all involves, it's really computational biology 47:22.000 --> 47:25.000 It involves all mathematics and informatics, statistics and all that stuff 47:26.000 --> 47:31.000 But if you want to take it out from there, you know much more about this than I do 47:32.000 --> 47:39.000 And actually, the first question that I have is, if you become a doctor, are you going to have to change your handle to call you Dr. Zygmunt? 47:39.000 --> 47:44.000 Well, that's why everybody is always saying, oh, are you really a doctor? 47:45.000 --> 47:50.000 Well, that's the idea, so that I'm only going to have to be like, yeah, it really is a doctor 47:51.000 --> 47:54.000 So, that's part of the whole handle, where that comes from 47:55.000 --> 47:59.000 But, I guess if we're going to get back to bioinformatics, probably the first thing that we should talk about 47:59.000 --> 48:04.000 It's not entirely computer related, but the first thing we should talk about is easily, you know, it's just DNA 48:05.000 --> 48:12.000 And one of the major uses for bioinformatics is the major indexes that are maintained of genetic sequences 48:13.000 --> 48:16.000 Probably the largest that's out there goes by the name of GenBank 48:17.000 --> 48:20.000 And that is maintained by the, I believe it's the National Institute of Health 48:20.000 --> 48:23.000 But, ugh, you know, I wish I would have read it down, because I have the URL 48:24.000 --> 48:26.000 I have a tiny URL, but I don't have the actual URL 48:27.000 --> 48:30.000 But, if you want to actually search GenBank, it's free and open to anybody 48:31.000 --> 48:33.000 You can get it at tinyurl.com 48:34.000 --> 48:36.000 Slash YS7FB 48:37.000 --> 48:42.000 And what that basically is, is the search engine of basically the Human Genome Project 48:42.000 --> 48:45.000 The Human Genome Project and other assorted gene sequences 48:46.000 --> 48:50.000 And you as a researcher can input into it a sequence of bases, of nucleotides 48:51.000 --> 48:52.000 And we're going to tell what that is in just a second 48:53.000 --> 48:59.000 And with that, you can get any matching sequences that exist, where they exist, what species they exist 49:00.000 --> 49:03.000 And what's the difference between that specific sequence in various species 49:03.000 --> 49:08.000 So anyway, for anybody who, it's been a while out of high school to talk about DNA 49:09.000 --> 49:11.000 It's a deoxyribonucleic acid 49:12.000 --> 49:15.000 We've all seen the pretty picture of the two spirals going up 49:16.000 --> 49:17.000 With the chain 49:18.000 --> 49:21.000 Yeah, and of course there's the four bases of DNA 49:22.000 --> 49:24.000 Adenine, thymine, guanine, and cytosine 49:25.000 --> 49:27.000 And that's what you see in all these gene banks, A, T, G, and C 49:28.000 --> 49:30.000 That's where it comes from, it's those four bases 49:30.000 --> 49:34.000 And they bind selectively, A to T, and G to C 49:35.000 --> 49:37.000 Of course there's reasons and times when that gets violated 49:38.000 --> 49:39.000 But that's not important for our discussion 49:40.000 --> 49:47.000 And it's the sequence of the bases that form the template for the transcription of the actual sequence of DNA code 49:48.000 --> 49:50.000 Into RNA, which is ribonucleic acid 49:51.000 --> 49:53.000 And what RNA does is that codes actually for protein 49:54.000 --> 49:55.000 The RNA itself is then copied 49:56.000 --> 49:59.000 And amino acids are put together and you're going to have a protein 49:59.000 --> 50:01.000 That protein is now going to be the actual phenotype 50:02.000 --> 50:04.000 So basically the whole mantra we're trying to get to here 50:05.000 --> 50:07.000 Is first DNA, RNA, protein 50:08.000 --> 50:11.000 When you have a change in the DNA, it's going to change the RNA 50:12.000 --> 50:13.000 And it will change the final outcome, the final protein 50:14.000 --> 50:17.000 And what they're doing with a lot of the bioinformatics is they can predict 50:18.000 --> 50:21.000 Okay, if we change this part of a protein, this is going to happen 50:21.000 --> 50:26.000 Some people have seen the, what's the major protein folding that's out there? 50:27.000 --> 50:28.000 Oh, protein folding at home 50:29.000 --> 50:30.000 Folding at home, yeah 50:31.000 --> 50:32.000 Folding at home, and that's not exactly the same thing 50:33.000 --> 50:34.000 But that's kind of, it's in the same realm 50:35.000 --> 50:36.000 It's a little bit more physics related 50:37.000 --> 50:38.000 But you could almost consider that bioinformatics 50:39.000 --> 50:42.000 It's really any use of computers to handle the massive amount of data 50:43.000 --> 50:45.000 That's really affiliated with life 50:46.000 --> 50:47.000 Okay 50:48.000 --> 50:49.000 So just before anyone gets the wrong idea 50:50.000 --> 50:52.000 We're not talking, you know, we're talking about DNA here 50:53.000 --> 50:56.000 But we're not talking that we're suggesting that people re-sequence their own DNA 50:57.000 --> 50:59.000 You know, because we're talking about sleep last week 51:00.000 --> 51:02.000 And people were thinking that we're, you know, endorsing polyphasic sleep here 51:03.000 --> 51:04.000 And I just want to get that out in the open 51:05.000 --> 51:06.000 And make sure no one's going to be doing it 51:06.000 --> 51:07.000 No one's going to be doing it, so 51:09.000 --> 51:11.000 We don't want to have, basically we're going to have like a bunch of like little kids like you 51:12.000 --> 51:13.000 You know, Island of Dr. Moreau 51:14.000 --> 51:15.000 Which is always cool 51:16.000 --> 51:17.000 Yeah 51:18.000 --> 51:21.000 But old Timmy, I re-sequence his DNA and he's now a five-ass monkey 51:22.000 --> 51:23.000 Five-ass 51:24.000 --> 51:28.000 But I'm sure what's really, what it comes down to is what is all this data really used for 51:29.000 --> 51:30.000 Yeah 51:31.000 --> 51:33.000 And really what it comes down to, the perfect example is a researcher 51:33.000 --> 51:35.000 They have a segment of some sort of DNA 51:36.000 --> 51:41.000 It has a specific sequence and they want to know where the sequence appears in the entire sequence 51:42.000 --> 51:43.000 Where it appears in the genetic map 51:44.000 --> 51:46.000 They want to know if their specific sequence is mutated slightly, you know 51:47.000 --> 51:48.000 Like maybe I have a T or I'm supposed to have an A 51:49.000 --> 51:52.000 Something like this can, like GenBank, can look through it 51:53.000 --> 51:55.000 You can feed it a sequence of 50 A's, T's, G's and C's 51:56.000 --> 51:58.000 And it'll find the closest sequence matches to it 51:59.000 --> 52:00.000 You can see maybe you have something that's mutated 52:00.000 --> 52:03.000 Maybe you have something from a different species, et cetera, et cetera 52:04.000 --> 52:07.000 And then you can bring this into a little bit more of the real-world applications 52:08.000 --> 52:10.000 You have something that's called a restriction endonuclease 52:11.000 --> 52:15.000 And that's a really fancy word to say a pair of scissors that cuts DNA 52:16.000 --> 52:20.000 It always cuts it at a specific point, which is a specific sequence 52:20.000 --> 52:23.000 You know, it'll always cut at A, T, G, G, G 52:24.000 --> 52:25.000 A, T, G, G 52:25.000 --> 52:26.000 They're usually paludromic sequences 52:27.000 --> 52:28.000 So I'm trying to remember A, T, G, C 52:29.000 --> 52:31.000 Okay, think of it the same way forwards and backwards, great 52:32.000 --> 52:36.000 But what you end up with is, let's say you're a researcher 52:37.000 --> 52:41.000 And you're going to use this specific restriction endonuclease to cut your sample of DNA 52:42.000 --> 52:46.000 It would probably be helpful to know if that sequence also appears in the middle of your DNA, wouldn't it? 52:47.000 --> 52:49.000 So that you don't end up cutting what you want to study in half 52:50.000 --> 52:51.000 That would kind of suck 52:52.000 --> 52:53.000 Totally 52:53.000 --> 52:56.000 So what you can do is you can turn to GenBank and say, hey, in this sequence 52:57.000 --> 52:59.000 I'm trying to determine what gene this is 53:00.000 --> 53:04.000 I think this might be BRCA1, which is breast cancer gene 1 53:05.000 --> 53:06.000 I want to study that 53:07.000 --> 53:08.000 So what's the exact sequence for that? 53:09.000 --> 53:10.000 It'll pop up, you know 53:11.000 --> 53:12.000 What do they call it? BRCA1? 53:13.000 --> 53:14.000 Oh, BRCA1 53:14.000 --> 53:16.000 Yeah, BRCA1 53:17.000 --> 53:19.000 And that's one of the genes that's linked to breast cancer 53:20.000 --> 53:21.000 But you know 53:22.000 --> 53:23.000 I mean, this just 53:24.000 --> 53:25.000 This always confuses me 53:26.000 --> 53:27.000 Like from the beginning when they're talking about 53:28.000 --> 53:31.000 Like, oh, we mapped everything 53:32.000 --> 53:35.000 I mean, they mapped all of the genes 53:36.000 --> 53:37.000 Now, what actually does that mean? 53:38.000 --> 53:39.000 Well, they haven't actually mapped all the genes 53:40.000 --> 53:42.000 And they don't know the function of every gene and every protein 53:42.000 --> 53:44.000 Okay, like for 53:45.000 --> 53:48.000 They took somebody's DNA and they mapped all the genes on it, right? 53:49.000 --> 53:54.000 They took the sequence and they were able to break down the sequence into its collections of A's, T's, G's, and C's 53:55.000 --> 53:59.000 Okay, but also at the same point, I mean, my collection of DNA is unique 53:59.000 --> 54:04.000 And it's not going to be, say, for example, you know, exactly matching their collection of DNA 54:05.000 --> 54:07.000 So what use does this actually serve? 54:08.000 --> 54:09.000 It's not that you're 54:10.000 --> 54:13.000 The genetic difference between two humans is really 54:14.000 --> 54:16.000 In the grand scheme of things, it's minuscule 54:16.000 --> 54:17.000 Okay 54:17.000 --> 54:20.000 The genetic difference between a human and a primate, a monkey, is only 54:20.000 --> 54:22.000 There's a 99% correlation 54:23.000 --> 54:27.000 You know, 99% of the sequences are pretty much exactly the same 54:28.000 --> 54:31.000 So there is going to be difference between human to human 54:31.000 --> 54:34.000 And they actually did have a paper 54:34.000 --> 54:39.000 I wish I could recall exactly where they got the DNA for the human genome project 54:40.000 --> 54:43.000 But it's such a small, like the only difference that you're going to have is you have boy or girl 54:43.000 --> 54:46.000 Of course you're going to have an X or a Y, you're going to have that extra 54:46.000 --> 54:48.000 You know, there are subtle differences, of course 54:48.000 --> 54:51.000 You know, eye color and everything that makes everybody look slightly different 54:51.000 --> 54:56.000 It's going to be a result of their genetic code, the phenotypes, the proteins that are produced 54:57.000 --> 55:01.000 But a lot of that, with bioinformatics, they're starting to catalog those differences 55:02.000 --> 55:04.000 Why is it that you have brown eyes versus green? 55:05.000 --> 55:08.000 You know, what is the exact change in the genetic code that's causing that? 55:09.000 --> 55:15.000 And something like that is very useful for, let's say, that there's also a degenerative ocular disorder 55:16.000 --> 55:17.000 That's causing cancer 55:17.000 --> 55:21.000 Now we can look at that exact gene sequence and say, hey, you know what? 55:22.000 --> 55:26.000 We see this correlation between people who have blue eyes and higher incidence of cancer, for instance 55:27.000 --> 55:28.000 Maybe there's something to do with the genetic sequence 55:29.000 --> 55:32.000 So they can look up that genetic sequence and they can see what's different 55:33.000 --> 55:34.000 They can experiment that on the lab 55:35.000 --> 55:38.000 And they have the ability to access this exact sequence 55:39.000 --> 55:42.000 When 20 years ago, if they wanted to do any sort of research like this 55:42.000 --> 55:47.000 It was millions of dollars to be able to build the libraries of genes 55:48.000 --> 55:53.000 And, you know, you'd have to try different restriction endonucleases to try to get the right sequence 55:54.000 --> 55:55.000 But with this, you can look it up 55:55.000 --> 55:56.000 It's at a couple of clicks 55:57.000 --> 55:58.000 Oh, oh, wait, there's a T here instead of a G 55:59.000 --> 56:00.000 I wonder what a difference that makes 56:00.000 --> 56:01.000 Let's see how that folds as a protein 56:02.000 --> 56:03.000 They can put that into a computer 56:04.000 --> 56:06.000 Granted, they have to be rather complicated computers, really sophisticated 56:07.000 --> 56:09.000 But that's why this is such an emerging market 56:10.000 --> 56:15.000 Right, yeah, you're not going to be running those on your, you know, 386 laptop from 1992 56:16.000 --> 56:17.000 This is going to require something pretty beefy 56:18.000 --> 56:21.000 Yeah, but you know, even those little computers help 56:22.000 --> 56:23.000 Just like a protein, or the folding at home 56:24.000 --> 56:25.000 They're just breaking it up into a little work unit 56:26.000 --> 56:27.000 Oh, yeah 56:28.000 --> 56:29.000 It's all very fascinating stuff 56:31.000 --> 56:34.000 Wide area distributed computing is just cool anywhere 56:34.000 --> 56:35.000 Mm-hmm 56:35.000 --> 56:36.000 Now, a question I have for you, Zygmunt 56:37.000 --> 56:38.000 And I don't know if I missed it 56:38.000 --> 56:39.000 Because I was busy trying to get the stream working correctly 56:40.000 --> 56:41.000 And I guess it's not really working 56:42.000 --> 56:43.000 But my question for you is 56:44.000 --> 56:45.000 Like, of the actual 56:46.000 --> 56:49.000 I mean, I know they've got the thing mapped out 56:50.000 --> 56:51.000 As far as the actual sequencing goes 56:54.000 --> 56:55.000 No, sorry, they've got a sequence 56:56.000 --> 56:59.000 But how many of the genes do they actually have, like, really mapped out now? 56:59.000 --> 57:00.000 And how many do they still have left to go? 57:01.000 --> 57:04.000 You know, I really, I can't quote a specific number 57:05.000 --> 57:06.000 Well, roughly 57:06.000 --> 57:07.000 I wish I could 57:08.000 --> 57:09.000 You know, I really, I can't even make an educated guess 57:10.000 --> 57:11.000 As to the number that has been sequenced 57:12.000 --> 57:13.000 I know if you talk about different species 57:14.000 --> 57:17.000 Like, if you look, one of the most used animals for genetic research 57:18.000 --> 57:19.000 Is Drosophila 57:20.000 --> 57:21.000 Yeah, is the fruit fly 57:21.000 --> 57:22.000 And that entire, it's only four chromosomes 57:23.000 --> 57:24.000 Every gene has been sequenced 57:25.000 --> 57:26.000 They know exactly what every single gene does 57:27.000 --> 57:28.000 They know where it is on the chromosome 57:29.000 --> 57:30.000 And they know if it's altered like this, this will happen 57:31.000 --> 57:32.000 If it's altered like that, that'll happen 57:33.000 --> 57:35.000 They could talk about the inheritance and all that 57:36.000 --> 57:40.000 But, you know, I can't give that exact number for the Human Genome Project 57:41.000 --> 57:42.000 I know they're definitely making leaps and strides 57:43.000 --> 57:45.000 And it's a huge area of research 57:46.000 --> 57:48.000 Because it really is, you get into the future of what's going to be medicine 57:49.000 --> 57:53.000 And you're going to start coming away from all these, all the different drugs and the different substances 57:53.000 --> 57:57.000 Where there's so many, so many bacteria that are resistant to antibiotics 57:58.000 --> 58:01.000 There are so many disorders that are genetic in nature 58:02.000 --> 58:06.000 It's going to start getting to a point where we're going to be using genetic engineering to cure disease on the fly 58:07.000 --> 58:08.000 You know, we're not quite there yet 58:09.000 --> 58:16.000 And we're looking at a lot of bunch of, a lot of immunological cures for different disorders 58:16.000 --> 58:20.000 A main one, because I hate to keep bringing it up and harping on it, but really cancer 58:21.000 --> 58:23.000 Cancer is going to be so difficult to treat 58:24.000 --> 58:25.000 Because it's different in every person 58:26.000 --> 58:28.000 And actually, and now as we're doing it real quick 58:29.000 --> 58:32.000 The reason that cancers are different is because they result from mutations 58:33.000 --> 58:35.000 You have to have at least five mutations in five different genes 58:36.000 --> 58:39.000 In order for a cell to revert to a cancerous state 58:40.000 --> 58:41.000 So it's going to grow uncontrollably 58:41.000 --> 58:44.000 You know, and that's why when you hear about people saying 58:45.000 --> 58:48.000 Oh, he has a, he has an increased risk of breast cancer 58:49.000 --> 58:50.000 Or not he 58:51.000 --> 58:52.000 Some men can get breast cancer as well 58:53.000 --> 58:54.000 I seem to recall that 58:55.000 --> 58:56.000 They do 58:57.000 --> 58:59.000 Well, it's not, it's not truly breast cancer 59:00.000 --> 59:02.000 It's cancer that's in the breast area, but it's some other form of cancer 59:03.000 --> 59:04.000 Breast cancer 59:05.000 --> 59:06.000 I actually had a job that used to deal with this 59:07.000 --> 59:09.000 And breast cancer can only be occurring in women 59:09.000 --> 59:15.000 Because it's, it's, it's, because I actually had to format all of these reports and everything 59:16.000 --> 59:19.000 And, like, you know, when you were talking about breast cancer 59:20.000 --> 59:22.000 You didn't want to put a, you didn't want to try to calculate out the male 59:23.000 --> 59:24.000 Because there was no data on that, so 59:25.000 --> 59:26.000 Take that, Susan G. Cummins 59:27.000 --> 59:28.000 Yeah 59:29.000 --> 59:33.000 Just like, just one of the lines of you didn't want to calculate out testicle cancer for the females 59:34.000 --> 59:35.000 Because there was going to be no data 59:35.000 --> 59:40.000 I, I don't recall that it'd be actually zero 59:41.000 --> 59:42.000 I thought it was a very, very small percentage 59:43.000 --> 59:45.000 But you could, I mean, I'll yield to you on this one 59:46.000 --> 59:50.000 Well, I, I don't, I, I, if I, if I remember correctly 59:51.000 --> 59:57.000 It's not, you, you, you, I mean, a man getting a cancer in his breast area 59:57.000 --> 01:00:02.000 But it's actually not breast cancer as the actual terminology goes 01:00:03.000 --> 01:00:04.000 In the same tissues, I'm sure 01:00:05.000 --> 01:00:08.000 I mean, yeah, yeah, because I believe breast cancer, breast cancer has to be within the mammary tissue of the female 01:00:09.000 --> 01:00:11.000 And we're completely drifting off topic here, so, yeah 01:00:12.000 --> 01:00:13.000 Back to bioinformatics 01:00:14.000 --> 01:00:15.000 Yeah 01:00:15.000 --> 01:00:21.000 But, really, the whole, the, the crux of the argument for bioinformatics is that it's, it's such a lot 01:00:22.000 --> 01:00:23.000 There's so much data to be processed 01:00:24.000 --> 01:00:26.000 You look at the, the human genome, it's absolutely gigantic 01:00:27.000 --> 01:00:29.000 You're talking about between 20 to 30,000 genes 01:00:30.000 --> 01:00:36.000 And each gene can be anywhere from, you know, a hundred bases up to a hundred thousand plus bases 01:00:37.000 --> 01:00:39.000 Tell me, how much, how much storage are we talking about? 01:00:40.000 --> 01:00:47.000 Well, GenBank, for one, has, has cataloged one, one gigabase of data 01:00:48.000 --> 01:00:51.000 Which is, think a gigabyte, and now you have gigabase, you know 01:00:52.000 --> 01:00:56.000 And it's really, it's gotten to the matter, and that's just on genetic sequences 01:00:57.000 --> 01:00:58.000 We could be talking about any other 01:00:59.000 --> 01:01:01.000 Are, all their bases are belong to them? 01:01:03.000 --> 01:01:05.000 All their bases are belong to them 01:01:05.000 --> 01:01:07.000 Oh, God, there's a t-shirt, right? 01:01:08.000 --> 01:01:12.000 There's a, do a, do like a DNA strand or something 01:01:13.000 --> 01:01:14.000 And then have, all your bases are belong to me 01:01:15.000 --> 01:01:18.000 That's a new shirt that you guys should come up with 01:01:19.000 --> 01:01:20.000 Yeah 01:01:21.000 --> 01:01:22.000 It'll be up with all the biology majors 01:01:23.000 --> 01:01:24.000 Yes 01:01:25.000 --> 01:01:26.000 You can have Watson and Crick on the shirt saying, all your bases are belong to me 01:01:27.000 --> 01:01:28.000 That's it, that's the shirt, right? 01:01:29.000 --> 01:01:32.000 Okay, so, I mean, so a gigabase, so that means like 01:01:32.000 --> 01:01:35.000 A billion bases, right? 01:01:35.000 --> 01:01:36.000 A billion bases, right? 01:01:36.000 --> 01:01:37.000 Yeah 01:01:38.000 --> 01:01:39.000 If that's what that, I guess 01:01:40.000 --> 01:01:41.000 Yeah, a billion base pairs 01:01:42.000 --> 01:01:43.000 I can't remember how much it was 01:01:44.000 --> 01:01:45.000 And that's just one database 01:01:45.000 --> 01:01:49.000 But I mean, GenBank does, it does take its data from several different locations 01:01:50.000 --> 01:01:54.000 A couple of them being the DNA Data Bank of Japan 01:01:55.000 --> 01:01:57.000 The European Molecular Biology Laboratory 01:01:58.000 --> 01:02:02.000 And GenBank at the National Center for Biotechnology Information 01:02:03.000 --> 01:02:05.000 So they're definitely, there's more than one database out there 01:02:06.000 --> 01:02:09.000 And GenBank just happens to be a search engine that will crawl through all these different ones 01:02:10.000 --> 01:02:13.000 And GenBank stands out because that's the one they really educate students about 01:02:13.000 --> 01:02:15.000 It's really the easiest to use 01:02:16.000 --> 01:02:19.000 And you can still get a whole lot of information 01:02:20.000 --> 01:02:21.000 And it's the same thing that researchers are using 01:02:22.000 --> 01:02:23.000 We're talking people who have their PhDs 01:02:24.000 --> 01:02:26.000 And beyond, people who are working on their Nobel Prizes 01:02:29.000 --> 01:02:31.000 When are you going to get your Nobel Prize? 01:02:32.000 --> 01:02:33.000 That's exactly what I want to know 01:02:33.000 --> 01:02:34.000 When am I going to get my Nobel Prize? 01:02:35.000 --> 01:02:36.000 I don't even want the money, I just want the prize 01:02:36.000 --> 01:02:38.000 So I can be like, my friends are going to come over 01:02:39.000 --> 01:02:42.000 And say, oh yes, this is my kitchen, this is my dining room, my Nobel Prize 01:02:45.000 --> 01:02:47.000 I mean, you've got to get chicks if you have a Nobel Prize 01:02:48.000 --> 01:02:49.000 Oh yeah 01:02:50.000 --> 01:02:51.000 Hey, do you want to check out my medal? 01:02:53.000 --> 01:02:54.000 They'll be like, ooh 01:02:57.000 --> 01:02:59.000 But there's also some information on the hardware that's used 01:03:00.000 --> 01:03:01.000 Or actually, rather, before the hardware 01:03:01.000 --> 01:03:04.000 I know they're using a lot of different scripting languages for stuff like that 01:03:04.000 --> 01:03:05.000 What's going on with that? 01:03:06.000 --> 01:03:07.000 Well, I mean, I was looking into this 01:03:08.000 --> 01:03:14.000 And apparently there's a fair share of, like, you know, regular languages that are actually being used to this 01:03:15.000 --> 01:03:22.000 Like, I mean, I actually knew that Perl was, you know, was actually used a lot in, like, you know, gene sequences 01:03:23.000 --> 01:03:24.000 But I actually had no clue what actually it is 01:03:24.000 --> 01:03:30.000 But what really shocked me is actually, well, two-fold, because A, because people actually use Python 01:03:31.000 --> 01:03:36.000 But what shocked me more was people were actually using Python for this type of stuff 01:03:37.000 --> 01:03:40.000 Which was, I mean, Perl and Python, yes, can do a lot of things 01:03:40.000 --> 01:03:50.000 But I did not expect it to actually get involved with gene sequencing and various other forms of, you know, biology type stuff 01:03:51.000 --> 01:03:52.000 I mean, I just use it as a data-munching language 01:03:53.000 --> 01:03:59.000 But I guess when you're dealing with, you know, gobs and gobs and gobs of data, it's a good thing 01:03:59.000 --> 01:04:09.000 But, like, you know, Perl, Python, they're often used to, you know, interface with the actual databases and parse output from the various programs 01:04:10.000 --> 01:04:16.000 However, it's actually interesting because Linux is actually used and open-source software is used a lot in this stuff 01:04:17.000 --> 01:04:23.000 Like, you know, communities of, you know, bioinformatics programmers have set up projects 01:04:23.000 --> 01:04:27.000 Like, you know, a couple of them that I just, you know, quickly want to rattle off here 01:04:28.000 --> 01:04:35.000 Mboss, M-B-M-B-O-S-S, Bioconductor, BioPearl, BioLinux, BioPython, BioRuby, and BioJava 01:04:36.000 --> 01:04:38.000 Hmm, I wonder where they get these names from, I don't know 01:04:39.000 --> 01:04:44.000 And what they do is they distribute shared programming tools and objects and file libraries 01:04:45.000 --> 01:04:46.000 That try to make bioinformatics easier 01:04:46.000 --> 01:04:51.000 And I actually found this cool article on O'Reilly about Perl and bioinformatics 01:04:52.000 --> 01:04:57.000 And it's HTTP colon slash tinyurl.com slash November Quebec Juliet 01:04:58.000 --> 01:05:01.000 Sorry, I've got a stuffy nose all of a sudden 01:05:02.000 --> 01:05:03.000 November Quebec Juliet 2 Echo 01:05:05.000 --> 01:05:08.000 Now, I knew in a while we actually had a bunker of an episode 01:05:09.000 --> 01:05:11.000 But I guess all good things must come to an end 01:05:11.000 --> 01:05:18.000 Actually, what really found cool is that I found an integrated software workbench 01:05:19.000 --> 01:05:23.000 And it actually has a lot of these tools described already 01:05:24.000 --> 01:05:27.000 And it's called, I'm not going to be able to pronounce it 01:05:28.000 --> 01:05:33.000 VigyanCD, V-I-G-Y-A-N-N-C-D 01:05:33.000 --> 01:05:37.000 It has all these tools 01:05:38.000 --> 01:05:41.000 And in itself it's open source bioinformatics workers 01:05:43.000 --> 01:05:45.000 And it's, apparently, it's quite complete 01:05:46.000 --> 01:05:50.000 I mean, I looked at it and I saw a nice like uh-huh-hah-huh-hah-huh-huh-hah-huh 01:05:50.000 --> 01:05:54.000 But, apparently, people are raving about it 01:05:54.000 --> 01:05:54.960 you actually do some Google in it, 01:05:55.000 --> 01:06:01.280 and it's available at vigyancd.org, two A's. 01:06:03.140 --> 01:06:05.840 They do also have, they have full Linux live CDs 01:06:05.840 --> 01:06:08.500 that are being used for this exact purpose, 01:06:08.680 --> 01:06:10.320 and something that's built into a lot of them 01:06:10.320 --> 01:06:12.300 is the ability to do distributed computing. 01:06:14.320 --> 01:06:15.600 Well, yeah, that's what part it is, 01:06:15.600 --> 01:06:21.900 and this program is actually part of a grid package 01:06:21.900 --> 01:06:23.860 so you can do your own little miniature grid computing. 01:06:24.000 --> 01:06:28.240 And it's cool, but I'm looking at it and going, 01:06:28.380 --> 01:06:30.680 I have no clue what the hell all this stuff is. 01:06:31.600 --> 01:06:33.460 I guess it's more along the lines of 01:06:33.460 --> 01:06:35.640 if you know exactly how to use the tools, 01:06:38.080 --> 01:06:40.220 this is actually good, 01:06:40.380 --> 01:06:43.100 but I'm just kind of going at it and saying, 01:06:43.100 --> 01:06:44.500 well, this looks impressive, 01:06:44.700 --> 01:06:46.660 but I actually have no idea actually how to use it. 01:06:46.720 --> 01:06:48.780 You can sequence DNA in the comfort of your own home. 01:06:49.900 --> 01:06:50.220 Woo-hoo! 01:06:50.740 --> 01:06:51.120 Yeah, I know. 01:06:51.120 --> 01:06:53.740 You can make all the searches on, 01:06:53.860 --> 01:06:54.700 especially GemBank. 01:06:54.780 --> 01:06:56.220 GemBank's really heavily used. 01:06:56.540 --> 01:06:57.660 You can, you know, just for kicks, 01:06:57.720 --> 01:06:59.020 you can throw in a couple of sequences 01:06:59.020 --> 01:07:01.180 and see what, it'll actually tell you the difference 01:07:01.180 --> 01:07:03.140 between, like, the relevance, 01:07:03.780 --> 01:07:05.440 you know, like, percent match. 01:07:05.700 --> 01:07:07.040 You see if maybe two proteins 01:07:07.040 --> 01:07:08.380 are going to interfere with each other. 01:07:08.380 --> 01:07:12.660 Well, actually, I did a search on that URL that you gave, 01:07:12.700 --> 01:07:13.820 and I did a search for boobies, 01:07:13.960 --> 01:07:15.780 and I was like, you know, 25 hits came up, so. 01:07:16.160 --> 01:07:16.520 Hey. 01:07:17.160 --> 01:07:18.960 Hey, I was like, all right, good for them. 01:07:20.080 --> 01:07:24.160 Hey, even biology majors need to have a daily dose. 01:07:24.860 --> 01:07:25.660 Apparently so. 01:07:25.660 --> 01:07:30.160 All right, so, 01:07:31.220 --> 01:07:32.500 since we already talked about software, 01:07:32.780 --> 01:07:33.560 you know, like, 01:07:34.080 --> 01:07:36.120 this is good for my own little home PC, 01:07:36.300 --> 01:07:38.940 but I assume that these diet pieces 01:07:38.940 --> 01:07:40.280 that are trying to, you know, 01:07:40.420 --> 01:07:42.620 sequence the entire human genome 01:07:42.620 --> 01:07:44.660 have slightly better hardware 01:07:44.660 --> 01:07:45.940 than my, you know, 01:07:46.120 --> 01:07:48.100 Athlon 1.7 gigahertz computer, 01:07:48.380 --> 01:07:49.620 at least I would hope, 01:07:49.900 --> 01:07:51.080 even if it's why it's taking so long. 01:07:51.900 --> 01:07:53.700 They do have some serious computers. 01:07:54.080 --> 01:07:54.700 One of them, 01:07:54.760 --> 01:07:55.800 they have a couple of nicknames. 01:07:56.820 --> 01:07:58.300 One of them that is used heavily, 01:07:58.440 --> 01:07:59.280 it's called Big Ben. 01:07:59.580 --> 01:08:03.540 It's a crazy XT3 MPP system. 01:08:03.700 --> 01:08:04.260 Oh, great. 01:08:04.580 --> 01:08:04.860 With a peak, 01:08:05.600 --> 01:08:06.420 yeah, with a peak, 01:08:06.580 --> 01:08:07.840 a peak teraflops, 01:08:07.940 --> 01:08:09.040 a 10 teraflops, 01:08:09.440 --> 01:08:10.920 which is a lot of calculation. 01:08:13.040 --> 01:08:14.120 And you just, I mean, 01:08:14.180 --> 01:08:14.960 we can ramble on. 01:08:15.120 --> 01:08:15.600 Another thing, 01:08:15.700 --> 01:08:17.620 they have an HP Alpha cluster 01:08:17.620 --> 01:08:18.540 that's being used. 01:08:18.620 --> 01:08:20.860 It's a cluster of more than 3,000 processors. 01:08:21.420 --> 01:08:22.920 And it has a peak speed 01:08:22.920 --> 01:08:23.900 of six teraflops. 01:08:23.980 --> 01:08:25.320 You actually see a lot of it 01:08:25.320 --> 01:08:26.060 is, because remember, 01:08:26.140 --> 01:08:27.180 there's a lot of universities 01:08:27.180 --> 01:08:29.360 and government agencies. 01:08:29.780 --> 01:08:30.460 Rather than buying 01:08:30.460 --> 01:08:31.740 a whole bunch of new hardware 01:08:31.740 --> 01:08:33.220 or buying a brand new supercomputer, 01:08:33.800 --> 01:08:34.820 they're just taking a bunch of, 01:08:34.880 --> 01:08:35.940 you know, normal computers 01:08:35.940 --> 01:08:36.980 and putting them in clusters. 01:08:38.360 --> 01:08:39.880 It makes my money very cheaper. 01:08:40.060 --> 01:08:41.100 Yeah, that was the entire point 01:08:41.100 --> 01:08:42.760 of the, what was it, 01:08:42.800 --> 01:08:45.020 the Virginia Tech XServe cluster 01:08:45.020 --> 01:08:46.880 when they actually came out 01:08:46.880 --> 01:08:47.700 with all new G, 01:08:47.900 --> 01:08:49.560 was it G4s or G5s? 01:08:49.560 --> 01:08:50.160 I forget now. 01:08:51.080 --> 01:08:52.400 I think it was G4s. 01:08:52.420 --> 01:08:53.740 I think it was like pre-G5. 01:08:53.840 --> 01:08:54.440 But when they came out 01:08:54.440 --> 01:08:55.280 with all that stuff, 01:08:56.800 --> 01:08:57.780 they just made, 01:08:57.920 --> 01:08:58.920 they tossed them all together 01:08:58.920 --> 01:08:59.520 and made a giant 01:08:59.520 --> 01:09:00.740 supercomputer cluster out of it. 01:09:00.800 --> 01:09:01.180 And actually, 01:09:01.360 --> 01:09:02.920 it looks very, very cool. 01:09:04.220 --> 01:09:04.840 It's like it's hot. 01:09:05.500 --> 01:09:07.160 Yeah, I'm sure it does. 01:09:08.240 --> 01:09:08.400 I mean, 01:09:08.500 --> 01:09:09.940 the clusters in itself 01:09:09.940 --> 01:09:11.020 are just incredibly easy 01:09:11.020 --> 01:09:11.420 to set up. 01:09:11.500 --> 01:09:11.680 I mean, 01:09:11.740 --> 01:09:12.800 I remember when 01:09:12.800 --> 01:09:14.040 I, you know, 01:09:14.040 --> 01:09:15.720 stumbled right upon 01:09:15.720 --> 01:09:17.560 the Beowulf clusters 01:09:17.560 --> 01:09:18.840 back in the day, 01:09:18.920 --> 01:09:19.620 like 2000. 01:09:20.480 --> 01:09:21.440 We had like a bunch 01:09:21.440 --> 01:09:22.520 of old 486s 01:09:22.520 --> 01:09:23.680 sitting there 01:09:23.680 --> 01:09:24.320 gathering dust 01:09:24.320 --> 01:09:24.860 waiting to be 01:09:24.860 --> 01:09:26.080 thrown out at work. 01:09:26.200 --> 01:09:27.640 So I wired them all up 01:09:27.640 --> 01:09:28.320 from underneath 01:09:28.320 --> 01:09:28.740 that hub, 01:09:28.880 --> 01:09:29.100 you know, 01:09:29.200 --> 01:09:31.360 installed all the 01:09:31.360 --> 01:09:32.560 Beowulf patches on there 01:09:32.560 --> 01:09:34.300 and they purred like kittens. 01:09:34.300 --> 01:09:35.680 And I was able to 01:09:35.680 --> 01:09:37.860 crack RC5 keys on them 01:09:37.860 --> 01:09:39.340 at amazingly fast rates. 01:09:42.300 --> 01:09:42.860 But yes, 01:09:42.940 --> 01:09:44.080 clusters are like 01:09:44.080 --> 01:09:44.940 very powerful 01:09:44.940 --> 01:09:45.920 and very easy to set up. 01:09:47.140 --> 01:09:48.000 And it's perfect. 01:09:48.300 --> 01:09:48.560 You know, 01:09:48.880 --> 01:09:50.400 a lot of the people 01:09:50.400 --> 01:09:51.060 in this field, 01:09:51.140 --> 01:09:52.100 they do have the money 01:09:52.100 --> 01:09:53.500 to buy the crazy computers. 01:09:54.080 --> 01:09:54.400 You know, 01:09:54.460 --> 01:09:55.800 the true supercomputers 01:09:55.800 --> 01:09:56.200 where, 01:09:56.400 --> 01:09:57.040 you know, 01:09:57.120 --> 01:09:58.360 it's got all the bells 01:09:58.360 --> 01:09:58.760 and whistles 01:09:58.760 --> 01:09:59.520 and it's, 01:09:59.580 --> 01:09:59.760 you know, 01:09:59.820 --> 01:10:00.940 half a million dollars 01:10:00.940 --> 01:10:01.840 or more. 01:10:02.320 --> 01:10:02.960 But I mean, 01:10:02.960 --> 01:10:03.380 a lot of it, 01:10:03.520 --> 01:10:04.240 a lot of the research 01:10:04.240 --> 01:10:05.120 it's all research. 01:10:05.600 --> 01:10:06.320 It's a lot of it 01:10:06.320 --> 01:10:07.580 is all being done 01:10:07.580 --> 01:10:08.260 from universities 01:10:08.260 --> 01:10:08.580 where, 01:10:08.700 --> 01:10:08.820 you know, 01:10:08.840 --> 01:10:09.280 if you're going to get 01:10:09.280 --> 01:10:10.040 that big grant, 01:10:10.260 --> 01:10:10.980 you don't want to spend 01:10:10.980 --> 01:10:11.900 it all on computers. 01:10:13.520 --> 01:10:13.880 Well, 01:10:13.960 --> 01:10:14.700 that we all know 01:10:14.700 --> 01:10:15.800 that biologists 01:10:15.800 --> 01:10:16.580 are very cheap. 01:10:20.180 --> 01:10:20.980 I wasn't aware 01:10:20.980 --> 01:10:21.720 of that stereotype. 01:10:22.520 --> 01:10:22.800 Oh, 01:10:22.860 --> 01:10:23.020 yeah, 01:10:23.080 --> 01:10:23.520 I knew that. 01:10:23.900 --> 01:10:24.240 You see, 01:10:24.360 --> 01:10:25.380 because biologists 01:10:25.380 --> 01:10:26.520 don't want to admit it, 01:10:26.560 --> 01:10:27.180 but we know. 01:10:27.480 --> 01:10:28.380 We know that biologists 01:10:28.380 --> 01:10:28.820 are cheap. 01:10:30.840 --> 01:10:31.200 Meanwhile, 01:10:32.040 --> 01:10:32.380 I mean, 01:10:32.400 --> 01:10:33.180 how many biologists 01:10:33.180 --> 01:10:33.600 do you know 01:10:33.600 --> 01:10:34.060 that are driving 01:10:34.060 --> 01:10:34.640 Rolls Royces? 01:10:35.960 --> 01:10:36.520 I don't know 01:10:36.520 --> 01:10:36.980 if that's them 01:10:36.980 --> 01:10:37.580 being cheap. 01:10:37.680 --> 01:10:38.080 It's just them 01:10:38.080 --> 01:10:38.980 being underpaid. 01:10:42.880 --> 01:10:43.200 Anyway. 01:10:45.660 --> 01:10:45.980 So, 01:10:46.060 --> 01:10:46.180 yeah, 01:10:46.260 --> 01:10:46.780 this was turning 01:10:46.780 --> 01:10:47.400 into a clunker 01:10:47.400 --> 01:10:47.900 of an episode. 01:10:48.000 --> 01:10:48.420 You want to just 01:10:48.420 --> 01:10:48.940 cut it here? 01:10:50.220 --> 01:10:50.540 No, 01:10:50.580 --> 01:10:50.940 not really. 01:10:50.980 --> 01:10:51.380 I think we're doing 01:10:51.380 --> 01:10:51.980 actually pretty well. 01:10:52.540 --> 01:10:52.860 So, 01:10:53.020 --> 01:10:53.260 okay, 01:10:53.360 --> 01:10:53.780 so we talked 01:10:53.780 --> 01:10:54.480 about Big Ben 01:10:54.480 --> 01:10:55.180 and, 01:10:55.840 --> 01:10:58.080 I mean, 01:10:58.160 --> 01:10:58.400 like, 01:10:58.400 --> 01:11:02.020 what all these 01:11:02.020 --> 01:11:02.980 computers just do 01:11:02.980 --> 01:11:03.540 is they just 01:11:03.540 --> 01:11:04.760 try to redo 01:11:04.760 --> 01:11:05.220 all these 01:11:05.220 --> 01:11:06.380 gene sequences 01:11:06.380 --> 01:11:07.240 and gene mapping 01:11:07.240 --> 01:11:07.840 and basically 01:11:07.840 --> 01:11:08.480 they've been doing 01:11:08.480 --> 01:11:09.300 this for five years 01:11:09.300 --> 01:11:09.760 and they're still 01:11:09.760 --> 01:11:10.340 not done yet? 01:11:11.340 --> 01:11:11.740 Well, 01:11:11.800 --> 01:11:12.140 actually, 01:11:12.280 --> 01:11:13.020 it could take, 01:11:13.560 --> 01:11:14.380 what a lot of the 01:11:14.380 --> 01:11:15.100 computers are doing, 01:11:15.260 --> 01:11:15.800 it's not that 01:11:15.800 --> 01:11:17.080 they're sequencing, 01:11:17.420 --> 01:11:18.180 the actual computers 01:11:18.180 --> 01:11:18.860 are doing all 01:11:18.860 --> 01:11:19.380 this sequencing. 01:11:19.840 --> 01:11:20.460 They do actually 01:11:20.460 --> 01:11:21.260 have machines 01:11:21.260 --> 01:11:22.480 that are used 01:11:22.480 --> 01:11:24.100 in order to 01:11:24.100 --> 01:11:25.300 sequence DNA. 01:11:25.500 --> 01:11:25.960 They have special 01:11:25.960 --> 01:11:26.760 machines for it. 01:11:26.760 --> 01:11:27.460 we can get into 01:11:27.460 --> 01:11:28.180 the whole process 01:11:28.180 --> 01:11:29.600 of the polymerase 01:11:29.600 --> 01:11:30.240 chain's reaction 01:11:30.240 --> 01:11:31.520 for duplicating DNA. 01:11:31.680 --> 01:11:32.040 It's not really 01:11:32.040 --> 01:11:32.560 necessary. 01:11:33.000 --> 01:11:33.480 But what most 01:11:33.480 --> 01:11:34.080 of these actual 01:11:34.080 --> 01:11:34.740 computers are doing 01:11:34.740 --> 01:11:35.320 is they're handling 01:11:35.320 --> 01:11:36.180 just the load 01:11:36.180 --> 01:11:37.320 of people searching 01:11:37.320 --> 01:11:38.040 the database. 01:11:39.240 --> 01:11:39.740 Because you think 01:11:39.740 --> 01:11:41.220 about all the load 01:11:41.220 --> 01:11:41.620 that's going to go 01:11:41.620 --> 01:11:41.720 in, 01:11:41.740 --> 01:11:42.160 because you have 01:11:42.160 --> 01:11:43.460 this one gigabit 01:11:43.460 --> 01:11:45.200 database that people 01:11:45.200 --> 01:11:45.680 are doing, 01:11:45.800 --> 01:11:46.080 you know, 01:11:46.140 --> 01:11:46.580 more or less 01:11:46.580 --> 01:11:47.720 like searches 01:11:47.720 --> 01:11:49.180 through the entire 01:11:49.180 --> 01:11:49.600 thing. 01:11:49.820 --> 01:11:50.420 And you have 01:11:50.420 --> 01:11:51.320 the entire research 01:11:51.320 --> 01:11:52.080 community doing 01:11:52.080 --> 01:11:53.120 these queries. 01:11:53.780 --> 01:11:53.960 You know, 01:11:54.060 --> 01:11:54.340 actually, 01:11:54.480 --> 01:11:55.200 the way GenBank 01:11:55.200 --> 01:11:55.880 works is it 01:11:55.880 --> 01:11:56.520 actually doesn't do 01:11:56.520 --> 01:11:56.940 your query 01:11:56.940 --> 01:11:57.340 as soon as 01:11:57.340 --> 01:11:57.820 you make it. 01:11:58.020 --> 01:11:58.560 It puts it 01:11:58.560 --> 01:11:59.040 in line. 01:11:59.440 --> 01:12:00.480 And it'll reload 01:12:00.480 --> 01:12:01.720 when your turn 01:12:01.720 --> 01:12:02.520 in line has come 01:12:02.520 --> 01:12:02.800 up. 01:12:03.280 --> 01:12:03.900 And that's one 01:12:03.900 --> 01:12:04.220 of the ways 01:12:04.220 --> 01:12:04.660 that they do 01:12:04.660 --> 01:12:05.060 their load 01:12:05.060 --> 01:12:05.480 balancing. 01:12:05.760 --> 01:12:05.940 You know, 01:12:06.000 --> 01:12:06.900 because it's a lot 01:12:06.900 --> 01:12:07.360 of information 01:12:07.360 --> 01:12:08.040 to process. 01:12:08.680 --> 01:12:09.040 Of course, 01:12:09.120 --> 01:12:10.220 there are some 01:12:10.220 --> 01:12:10.640 things that you 01:12:10.640 --> 01:12:11.340 can do entirely 01:12:11.340 --> 01:12:11.920 in the computer 01:12:11.920 --> 01:12:12.320 world, 01:12:12.420 --> 01:12:12.840 such as, 01:12:12.860 --> 01:12:13.040 you know, 01:12:13.040 --> 01:12:13.380 some of the 01:12:13.380 --> 01:12:14.120 protein folding. 01:12:14.600 --> 01:12:15.080 But that has 01:12:15.080 --> 01:12:15.800 to be validated 01:12:15.800 --> 01:12:17.340 and, you know, 01:12:17.360 --> 01:12:17.980 all the theories 01:12:17.980 --> 01:12:18.640 of how the 01:12:18.640 --> 01:12:19.280 computer program 01:12:19.280 --> 01:12:19.740 is working 01:12:19.740 --> 01:12:20.560 has to be proven 01:12:20.560 --> 01:12:21.880 to be the way 01:12:21.880 --> 01:12:22.480 things exist 01:12:22.480 --> 01:12:23.360 in the real world. 01:12:23.620 --> 01:12:24.140 Because we all 01:12:24.140 --> 01:12:24.360 know, 01:12:24.420 --> 01:12:24.600 you know, 01:12:24.600 --> 01:12:25.700 academic and 01:12:25.700 --> 01:12:26.800 theory versus, 01:12:27.640 --> 01:12:27.940 you know, 01:12:28.060 --> 01:12:29.200 actuality is never 01:12:29.200 --> 01:12:30.820 a hand-to-hand 01:12:30.820 --> 01:12:32.740 or an exact 01:12:32.740 --> 01:12:33.520 same transition. 01:12:35.020 --> 01:12:35.460 So, 01:12:35.500 --> 01:12:35.940 so wait, 01:12:36.060 --> 01:12:37.260 you kind of 01:12:37.260 --> 01:12:37.640 mentioned this 01:12:37.640 --> 01:12:38.020 in passing, 01:12:38.140 --> 01:12:38.440 but like, 01:12:38.520 --> 01:12:38.900 for example, 01:12:38.900 --> 01:12:39.460 when I'm doing 01:12:39.460 --> 01:12:39.980 something like 01:12:39.980 --> 01:12:40.680 protein folding 01:12:40.680 --> 01:12:41.160 or I'm doing 01:12:41.160 --> 01:12:41.520 like something 01:12:41.520 --> 01:12:41.960 of folding at 01:12:41.960 --> 01:12:42.140 home, 01:12:42.560 --> 01:12:43.540 I'm doing it 01:12:43.540 --> 01:12:43.860 but someone 01:12:43.860 --> 01:12:44.440 actually has to 01:12:44.440 --> 01:12:45.360 re-verify my work? 01:12:45.740 --> 01:12:46.200 They don't have 01:12:46.200 --> 01:12:46.780 to re-verify 01:12:46.780 --> 01:12:47.360 every single 01:12:47.360 --> 01:12:48.080 calculation that 01:12:48.080 --> 01:12:48.420 you do, 01:12:48.820 --> 01:12:49.580 but as a good 01:12:49.580 --> 01:12:50.020 researcher, 01:12:50.400 --> 01:12:51.020 you can't just 01:12:51.020 --> 01:12:51.840 blindly accept 01:12:51.840 --> 01:12:52.160 data. 01:12:52.160 --> 01:12:53.200 Yeah, 01:12:53.260 --> 01:12:53.620 I guess it 01:12:53.620 --> 01:12:53.980 kind of makes 01:12:53.980 --> 01:12:54.700 sense in the 01:12:54.700 --> 01:12:55.660 actual long run, 01:12:55.780 --> 01:12:57.020 but that does 01:12:57.020 --> 01:12:57.680 kind of hurt my 01:12:57.680 --> 01:12:57.980 feelings, 01:12:58.080 --> 01:12:58.460 like they don't 01:12:58.460 --> 01:12:58.940 trust me. 01:13:00.780 --> 01:13:01.500 I'm honest, 01:13:01.680 --> 01:13:02.500 I'm a boy scout. 01:13:04.840 --> 01:13:05.580 It's not all, 01:13:05.740 --> 01:13:05.800 like, 01:13:05.880 --> 01:13:06.460 they're not going 01:13:06.460 --> 01:13:06.840 to have to 01:13:06.840 --> 01:13:07.320 re-go, 01:13:07.560 --> 01:13:09.020 go ahead and 01:13:09.020 --> 01:13:09.780 re-check the 01:13:09.780 --> 01:13:10.140 way that the 01:13:10.140 --> 01:13:10.880 protein is folding 01:13:10.880 --> 01:13:11.700 and check the 01:13:11.700 --> 01:13:12.740 chaperone molecules 01:13:12.740 --> 01:13:13.220 and et cetera, 01:13:13.300 --> 01:13:13.460 et cetera. 01:13:13.560 --> 01:13:13.740 You know, 01:13:13.780 --> 01:13:14.140 they're just going 01:13:14.140 --> 01:13:15.140 to test the 01:13:15.140 --> 01:13:16.420 interactions and 01:13:16.420 --> 01:13:16.900 make sure that 01:13:16.900 --> 01:13:17.580 things are behaving 01:13:17.580 --> 01:13:18.100 the way they 01:13:18.100 --> 01:13:18.320 should. 01:13:19.080 --> 01:13:19.660 There's such 01:13:19.660 --> 01:13:20.120 thing called 01:13:20.120 --> 01:13:21.160 chaperone molecules? 01:13:21.160 --> 01:13:21.660 Oh, 01:13:21.760 --> 01:13:22.420 chaperone proteins? 01:13:22.520 --> 01:13:22.880 They help 01:13:22.880 --> 01:13:23.660 proteins fold. 01:13:23.960 --> 01:13:24.300 They're also 01:13:24.300 --> 01:13:24.780 called heat 01:13:24.780 --> 01:13:25.600 shock proteins, 01:13:26.040 --> 01:13:26.680 which is another 01:13:26.680 --> 01:13:28.080 emerging technology 01:13:28.080 --> 01:13:28.560 in cancer 01:13:28.560 --> 01:13:29.100 treatments. 01:13:30.940 --> 01:13:31.360 Hot damn, 01:13:31.440 --> 01:13:31.980 I always liked 01:13:31.980 --> 01:13:32.780 biology back in 01:13:32.780 --> 01:13:33.180 high school, 01:13:33.320 --> 01:13:33.680 but I never 01:13:33.680 --> 01:13:34.300 actually got into 01:13:34.300 --> 01:13:34.460 it, 01:13:34.520 --> 01:13:34.840 and I really 01:13:34.840 --> 01:13:35.260 kind of miss 01:13:35.260 --> 01:13:35.700 that now. 01:13:36.780 --> 01:13:37.100 And actually, 01:13:37.300 --> 01:13:38.800 the entire world 01:13:38.800 --> 01:13:39.180 has kind of 01:13:39.180 --> 01:13:39.900 blown me by 01:13:39.900 --> 01:13:40.560 from high school 01:13:40.560 --> 01:13:41.040 biology, 01:13:41.180 --> 01:13:41.460 and we're 01:13:41.460 --> 01:13:41.880 talking about 01:13:41.880 --> 01:13:42.440 highly advanced 01:13:42.440 --> 01:13:42.840 stuff here. 01:13:44.740 --> 01:13:45.400 But anyway, 01:13:46.020 --> 01:13:47.180 so we also 01:13:47.180 --> 01:13:47.780 have a note of 01:13:47.780 --> 01:13:48.140 some other 01:13:48.140 --> 01:13:48.860 database on here 01:13:48.860 --> 01:13:49.820 called ChemFinder. 01:13:49.820 --> 01:13:51.560 What ChemFinder 01:13:51.560 --> 01:13:51.900 is, 01:13:51.940 --> 01:13:53.280 it's not 01:13:53.280 --> 01:13:54.440 truly bioinformatics, 01:13:54.540 --> 01:13:54.900 it's a lot 01:13:54.900 --> 01:13:55.360 more of just 01:13:55.360 --> 01:13:56.140 a great database 01:13:56.140 --> 01:13:56.660 that's being 01:13:56.660 --> 01:13:57.320 used a lot 01:13:57.320 --> 01:13:58.120 in the field 01:13:58.120 --> 01:13:58.700 of chemistry. 01:13:59.420 --> 01:14:00.140 What it is, 01:14:00.180 --> 01:14:01.240 is it's basically 01:14:01.240 --> 01:14:02.620 a huge depository, 01:14:02.620 --> 01:14:03.160 ooh, 01:14:03.320 --> 01:14:04.020 depository, 01:14:04.180 --> 01:14:04.500 what? 01:14:04.980 --> 01:14:06.300 A huge depository, 01:14:06.300 --> 01:14:09.640 a huge depository 01:14:09.640 --> 01:14:11.880 for information 01:14:11.880 --> 01:14:12.500 about various 01:14:12.500 --> 01:14:12.900 chemicals, 01:14:13.040 --> 01:14:13.660 various substances, 01:14:13.960 --> 01:14:14.180 you know, 01:14:14.220 --> 01:14:14.940 it includes a lot 01:14:14.940 --> 01:14:15.360 of the vital 01:14:15.360 --> 01:14:15.900 statistics, 01:14:16.300 --> 01:14:16.880 like boiling 01:14:16.880 --> 01:14:17.260 point, 01:14:17.380 --> 01:14:17.920 melting point, 01:14:18.040 --> 01:14:18.740 vapor pressure, 01:14:19.300 --> 01:14:19.700 et cetera, 01:14:19.800 --> 01:14:20.120 et cetera. 01:14:20.580 --> 01:14:21.620 But that's done 01:14:21.620 --> 01:14:22.960 by Cambridge Soft, 01:14:23.420 --> 01:14:23.900 and what's nice 01:14:23.900 --> 01:14:24.440 about them is 01:14:24.440 --> 01:14:24.980 they actually give 01:14:24.980 --> 01:14:25.160 you, 01:14:25.300 --> 01:14:26.060 you can do five 01:14:26.060 --> 01:14:26.740 free searches 01:14:26.740 --> 01:14:27.660 without registering, 01:14:28.020 --> 01:14:28.400 and then you have 01:14:28.400 --> 01:14:28.900 to register, 01:14:29.140 --> 01:14:29.700 but you can keep 01:14:29.700 --> 01:14:30.300 doing searches. 01:14:30.980 --> 01:14:31.740 And for anybody 01:14:31.740 --> 01:14:32.420 who's listening 01:14:32.420 --> 01:14:34.460 and is in school 01:14:34.460 --> 01:14:35.920 and has a chemistry 01:14:35.920 --> 01:14:37.080 class where you 01:14:37.080 --> 01:14:37.880 have to do lab 01:14:37.880 --> 01:14:38.360 write-ups, 01:14:38.440 --> 01:14:38.860 and et cetera, 01:14:38.960 --> 01:14:39.300 et cetera, 01:14:39.500 --> 01:14:40.280 this is an excellent 01:14:40.280 --> 01:14:41.080 resource for that 01:14:41.080 --> 01:14:41.600 sort of thing. 01:14:42.680 --> 01:14:43.560 The internet's making 01:14:43.560 --> 01:14:44.260 the kids see it 01:14:44.260 --> 01:14:44.860 be soft. 01:14:45.000 --> 01:14:45.120 I mean, 01:14:45.140 --> 01:14:45.640 I remember having 01:14:45.640 --> 01:14:46.220 to do all this 01:14:46.220 --> 01:14:46.880 shit in books, 01:14:47.520 --> 01:14:48.080 looking up like, 01:14:48.180 --> 01:14:48.500 oh, 01:14:48.660 --> 01:14:49.060 look at that, 01:14:49.100 --> 01:14:49.620 the specific 01:14:49.620 --> 01:14:50.480 gravity of this 01:14:50.480 --> 01:14:51.300 material is a 01:14:51.300 --> 01:14:52.040 whole lot bigger. 01:14:54.280 --> 01:14:54.640 Well, 01:14:54.680 --> 01:14:55.120 that would be 01:14:55.120 --> 01:14:55.800 all the answers. 01:14:56.700 --> 01:14:56.960 Why don't you 01:14:56.960 --> 01:14:57.360 just go to 01:14:57.360 --> 01:14:58.180 ChemFinder and 01:14:58.180 --> 01:14:58.860 find all this 01:14:58.860 --> 01:15:00.280 crazy shit? 01:15:00.640 --> 01:15:01.080 Online, 01:15:01.160 --> 01:15:01.720 automatically. 01:15:02.720 --> 01:15:03.900 Back in my day, 01:15:04.460 --> 01:15:05.520 when I was your age, 01:15:05.560 --> 01:15:07.040 uphill both ways, 01:15:07.740 --> 01:15:08.840 uphill both ways 01:15:08.840 --> 01:15:09.540 in the snow, 01:15:10.380 --> 01:15:10.940 in the middle 01:15:10.940 --> 01:15:11.420 of the summer, 01:15:12.200 --> 01:15:12.980 had to slaughter 01:15:12.980 --> 01:15:13.920 an animal on my 01:15:13.920 --> 01:15:14.420 way to school 01:15:14.420 --> 01:15:15.040 to have lunch 01:15:15.040 --> 01:15:15.820 without shoes. 01:15:17.200 --> 01:15:17.640 Yes. 01:15:18.700 --> 01:15:19.180 Shoes? 01:15:19.260 --> 01:15:19.640 I didn't even 01:15:19.640 --> 01:15:20.260 have feet. 01:15:20.440 --> 01:15:21.020 All the way 01:15:21.020 --> 01:15:21.420 on a road 01:15:21.420 --> 01:15:22.020 made entirely 01:15:22.020 --> 01:15:22.880 of razor blades. 01:15:24.040 --> 01:15:24.420 Yes, 01:15:24.440 --> 01:15:25.560 and I enjoyed it. 01:15:25.700 --> 01:15:26.360 And then afterwards 01:15:26.360 --> 01:15:26.780 walked through 01:15:26.780 --> 01:15:27.120 the rubbing 01:15:27.120 --> 01:15:27.840 alcohol river. 01:15:29.460 --> 01:15:29.920 All right. 01:15:30.800 --> 01:15:31.020 So, 01:15:31.120 --> 01:15:31.500 I mean, 01:15:31.620 --> 01:15:32.560 we kind of 01:15:32.560 --> 01:15:33.080 like really 01:15:33.080 --> 01:15:34.040 basically glossed 01:15:34.040 --> 01:15:34.560 over a lot of 01:15:34.560 --> 01:15:34.920 stuff here. 01:15:35.020 --> 01:15:35.160 I mean, 01:15:35.220 --> 01:15:36.320 this is a very 01:15:36.320 --> 01:15:37.160 intense field 01:15:37.160 --> 01:15:37.560 and, 01:15:38.040 --> 01:15:38.240 I mean, 01:15:38.260 --> 01:15:38.640 we're not going 01:15:38.640 --> 01:15:38.920 to be able 01:15:38.920 --> 01:15:39.440 to cover all 01:15:39.440 --> 01:15:39.820 the stuff 01:15:39.820 --> 01:15:40.260 on one night, 01:15:40.320 --> 01:15:40.640 but I think 01:15:40.640 --> 01:15:41.220 we did kind 01:15:41.220 --> 01:15:42.660 of cover a lot 01:15:42.660 --> 01:15:43.220 of the basics 01:15:43.220 --> 01:15:43.620 and what 01:15:43.620 --> 01:15:44.800 bioinformatics is 01:15:44.800 --> 01:15:45.980 and how you 01:15:45.980 --> 01:15:46.620 can actually use 01:15:46.620 --> 01:15:47.280 all this stuff 01:15:47.280 --> 01:15:48.080 and why it 01:15:48.080 --> 01:15:48.520 actually be 01:15:48.520 --> 01:15:49.220 interesting to 01:15:49.220 --> 01:15:49.660 some people. 01:15:50.180 --> 01:15:50.500 And I'm sure 01:15:50.500 --> 01:15:50.900 there's a lot 01:15:50.900 --> 01:15:51.380 of people out 01:15:51.380 --> 01:15:51.780 there when we're 01:15:51.780 --> 01:15:52.280 talking about 01:15:52.280 --> 01:15:53.440 shaperone proteins 01:15:53.440 --> 01:15:55.400 and specific 01:15:55.400 --> 01:15:56.160 densities, 01:15:56.380 --> 01:15:56.680 sorry, 01:15:56.760 --> 01:15:57.500 specific gravity 01:15:57.500 --> 01:15:58.140 and all that 01:15:58.140 --> 01:15:58.660 kind of stuff 01:15:58.660 --> 01:15:59.780 and RNA, 01:16:00.000 --> 01:16:00.220 DNA, 01:16:00.420 --> 01:16:00.740 and I'm sure 01:16:00.740 --> 01:16:01.120 there are a lot 01:16:01.120 --> 01:16:01.560 of people just 01:16:01.560 --> 01:16:02.260 sleeping right now, 01:16:02.340 --> 01:16:02.900 but hey, 01:16:03.680 --> 01:16:04.640 screw you all. 01:16:06.200 --> 01:16:07.020 It's a nice thing 01:16:07.020 --> 01:16:07.560 to think about 01:16:07.560 --> 01:16:08.220 for a career. 01:16:08.460 --> 01:16:08.620 You know, 01:16:08.700 --> 01:16:09.340 if you're somebody 01:16:09.340 --> 01:16:09.800 who's really 01:16:09.800 --> 01:16:10.740 interested in computers 01:16:10.740 --> 01:16:11.340 and you're also 01:16:11.340 --> 01:16:11.960 really interested 01:16:11.960 --> 01:16:12.660 in biology, 01:16:13.200 --> 01:16:14.100 it's something 01:16:14.100 --> 01:16:14.640 to consider 01:16:14.640 --> 01:16:15.300 because you get 01:16:15.300 --> 01:16:16.080 a chance to work 01:16:16.080 --> 01:16:16.900 with medicine, 01:16:17.240 --> 01:16:17.840 you get to help 01:16:17.840 --> 01:16:18.500 people with what 01:16:18.500 --> 01:16:18.960 you're doing, 01:16:19.560 --> 01:16:20.460 and you get to 01:16:20.460 --> 01:16:20.940 handle some 01:16:20.940 --> 01:16:21.200 really, 01:16:21.280 --> 01:16:21.920 really nice 01:16:21.920 --> 01:16:23.420 computers and 01:16:23.420 --> 01:16:24.100 do a lot 01:16:24.100 --> 01:16:25.020 of data crunching. 01:16:25.920 --> 01:16:26.600 If you like 01:16:26.600 --> 01:16:27.200 data crunching, 01:16:27.300 --> 01:16:27.860 this seems to be 01:16:27.860 --> 01:16:28.560 the field for you. 01:16:28.700 --> 01:16:29.000 And actually, 01:16:29.460 --> 01:16:31.040 before I left 01:16:31.040 --> 01:16:31.480 work today, 01:16:31.580 --> 01:16:32.340 I actually set up 01:16:32.340 --> 01:16:33.340 to download 01:16:33.340 --> 01:16:34.240 that bootable CD 01:16:34.240 --> 01:16:35.260 and I am going 01:16:35.260 --> 01:16:35.920 to try and play 01:16:35.920 --> 01:16:36.520 with it and see 01:16:36.520 --> 01:16:36.820 what the hell 01:16:36.820 --> 01:16:37.520 I can do with it. 01:16:39.020 --> 01:16:39.820 It's interesting 01:16:39.820 --> 01:16:40.440 and it just seems 01:16:40.440 --> 01:16:40.860 to be like 01:16:40.860 --> 01:16:41.540 massive data. 01:16:41.920 --> 01:16:43.060 I do enjoy 01:16:43.060 --> 01:16:44.260 just crunching 01:16:44.260 --> 01:16:45.040 massive databases 01:16:45.040 --> 01:16:45.680 for some reason. 01:16:45.820 --> 01:16:46.200 I'm a sick, 01:16:46.320 --> 01:16:47.140 sad person like that. 01:16:47.680 --> 01:16:47.840 I mean, 01:16:47.880 --> 01:16:48.220 look at me. 01:16:48.320 --> 01:16:49.340 I keep a database 01:16:49.340 --> 01:16:49.980 of payphones. 01:16:51.140 --> 01:16:52.840 But it's fun 01:16:52.840 --> 01:16:53.540 to crunch numbers 01:16:53.540 --> 01:16:54.100 in my opinion. 01:16:54.380 --> 01:16:56.240 If you do enjoy 01:16:56.240 --> 01:16:56.880 this sort of thing, 01:16:56.980 --> 01:16:57.780 I think this is 01:16:57.780 --> 01:16:58.200 going to be 01:16:58.200 --> 01:16:58.920 a very interesting 01:16:58.920 --> 01:17:00.940 way of interesting 01:17:00.940 --> 01:17:01.580 things for you 01:17:01.580 --> 01:17:01.900 to do. 01:17:03.580 --> 01:17:04.320 And I didn't mean 01:17:04.320 --> 01:17:04.900 screw you all. 01:17:05.020 --> 01:17:05.260 Please, 01:17:05.340 --> 01:17:05.520 you know, 01:17:05.580 --> 01:17:06.340 tune in next week. 01:17:06.400 --> 01:17:06.920 We love you, 01:17:07.080 --> 01:17:07.600 listeners, 01:17:08.120 --> 01:17:08.740 all that stuff. 01:17:10.440 --> 01:17:10.860 Look at that. 01:17:10.940 --> 01:17:11.600 I'm Strom dropping 01:17:11.600 --> 01:17:12.180 off on me. 01:17:12.260 --> 01:17:12.820 I'm insulting 01:17:12.820 --> 01:17:13.240 all of our 01:17:13.240 --> 01:17:13.680 listener bands. 01:17:15.220 --> 01:17:15.700 Yeah. 01:17:16.020 --> 01:17:16.260 Yeah. 01:17:16.920 --> 01:17:17.360 Anyway, 01:17:18.140 --> 01:17:19.200 announcements. 01:17:20.300 --> 01:17:20.640 Strom, 01:17:20.700 --> 01:17:20.920 do you have 01:17:20.920 --> 01:17:21.200 announcements? 01:17:22.660 --> 01:17:23.540 Layer 1. 01:17:24.460 --> 01:17:25.240 Two and a half 01:17:25.240 --> 01:17:25.920 weeks from now. 01:17:26.880 --> 01:17:27.820 Layer1.info. 01:17:27.820 --> 01:17:27.940 Oh, really? 01:17:28.220 --> 01:17:28.580 Yes. 01:17:30.500 --> 01:17:31.320 I'm talking. 01:17:31.500 --> 01:17:32.060 Come see my 01:17:32.060 --> 01:17:32.680 awesome talk. 01:17:34.680 --> 01:17:35.780 What weekend 01:17:35.780 --> 01:17:36.220 is that? 01:17:36.280 --> 01:17:36.800 That's Tax 01:17:36.800 --> 01:17:37.320 Day weekend, 01:17:37.440 --> 01:17:38.300 April 15th and 01:17:38.300 --> 01:17:38.680 16th. 01:17:38.720 --> 01:17:39.460 Tax Day weekend? 01:17:39.460 --> 01:17:40.540 Okay, so 01:17:40.540 --> 01:17:41.300 in the weekend 01:17:41.300 --> 01:17:42.020 before that, 01:17:42.100 --> 01:17:42.600 if you want to 01:17:42.600 --> 01:17:43.040 head over to 01:17:43.040 --> 01:17:43.520 Ohio, 01:17:44.420 --> 01:17:45.560 Nauticon is 01:17:45.560 --> 01:17:45.900 coming, 01:17:46.700 --> 01:17:47.080 and that's in 01:17:47.080 --> 01:17:47.460 Cleveland. 01:17:48.020 --> 01:17:48.580 You see beautiful 01:17:48.580 --> 01:17:49.400 downtown Cleveland. 01:17:50.960 --> 01:17:51.440 Droops is 01:17:51.440 --> 01:17:51.880 presenting. 01:17:53.360 --> 01:17:54.300 I think Droops is 01:17:54.300 --> 01:17:54.580 presenting, 01:17:54.580 --> 01:17:54.900 isn't he? 01:17:55.100 --> 01:17:55.280 Yeah. 01:17:55.380 --> 01:17:55.820 I think he's 01:17:55.820 --> 01:17:56.380 been also with 01:17:56.380 --> 01:17:56.860 Ponyboy. 01:17:57.600 --> 01:17:57.860 Yeah, 01:17:57.940 --> 01:17:58.340 Droops, 01:17:58.460 --> 01:17:58.900 Ponyboy, 01:17:59.020 --> 01:17:59.560 Nightlord, 01:18:00.840 --> 01:18:01.480 a lot of the 01:18:01.480 --> 01:18:02.400 Infonomicon crew 01:18:02.400 --> 01:18:03.100 over there on 01:18:03.100 --> 01:18:03.800 PoundInfonomicon 01:18:03.800 --> 01:18:05.360 on irc.freeno.net. 01:18:06.040 --> 01:18:06.920 So head on over 01:18:06.920 --> 01:18:07.180 there, 01:18:07.300 --> 01:18:08.000 show your support, 01:18:08.000 --> 01:18:10.000 and it seems to 01:18:10.000 --> 01:18:10.340 be a very 01:18:10.340 --> 01:18:11.460 interesting thing. 01:18:12.380 --> 01:18:12.920 It's not 01:18:12.920 --> 01:18:13.600 specifically a 01:18:13.600 --> 01:18:14.160 hacker convention 01:18:14.160 --> 01:18:14.600 from what I 01:18:14.600 --> 01:18:14.940 can tell. 01:18:15.560 --> 01:18:16.380 There's far too 01:18:16.380 --> 01:18:17.000 many girls in 01:18:17.000 --> 01:18:17.340 the pictures. 01:18:20.280 --> 01:18:21.020 Other than that, 01:18:21.120 --> 01:18:21.720 it seems pretty 01:18:21.720 --> 01:18:21.920 cool. 01:18:22.180 --> 01:18:22.900 They actually have 01:18:22.900 --> 01:18:23.260 something, 01:18:24.740 --> 01:18:25.240 one of the 01:18:25.240 --> 01:18:25.700 contests they 01:18:25.700 --> 01:18:28.280 had was transmit 01:18:28.280 --> 01:18:28.960 data over 01:18:28.960 --> 01:18:29.500 anything you 01:18:29.500 --> 01:18:29.760 can. 01:18:29.840 --> 01:18:30.220 I don't know 01:18:30.220 --> 01:18:30.660 what the exact 01:18:30.660 --> 01:18:31.180 title is, 01:18:31.180 --> 01:18:33.120 but use your 01:18:33.120 --> 01:18:33.820 most interesting 01:18:33.820 --> 01:18:34.420 creation to 01:18:34.420 --> 01:18:35.160 transmit data and 01:18:35.160 --> 01:18:35.720 you get points. 01:18:35.720 --> 01:18:36.800 because, 01:18:36.860 --> 01:18:37.040 you know, 01:18:37.120 --> 01:18:37.800 Ethernet isn't 01:18:37.800 --> 01:18:38.260 everything. 01:18:38.440 --> 01:18:38.760 I think there's 01:18:38.760 --> 01:18:39.300 your tagline. 01:18:40.320 --> 01:18:41.000 Bring back the 01:18:41.000 --> 01:18:41.480 string and 01:18:41.480 --> 01:18:41.840 can. 01:18:42.780 --> 01:18:43.440 They actually 01:18:43.440 --> 01:18:43.780 do that. 01:18:43.880 --> 01:18:44.520 If you do 01:18:44.520 --> 01:18:44.980 something with 01:18:44.980 --> 01:18:45.340 a string and 01:18:45.340 --> 01:18:45.520 can, 01:18:45.580 --> 01:18:46.000 you get 10 01:18:46.000 --> 01:18:46.240 points. 01:18:46.960 --> 01:18:47.480 I wonder if 01:18:47.480 --> 01:18:47.800 you could do 01:18:47.800 --> 01:18:47.920 that. 01:18:47.920 --> 01:18:48.160 See, 01:18:48.220 --> 01:18:48.760 now I have to 01:18:48.760 --> 01:18:49.400 go just so I 01:18:49.400 --> 01:18:50.100 can do that. 01:18:51.580 --> 01:18:52.020 It'd be 01:18:52.020 --> 01:18:52.760 really interesting. 01:18:54.540 --> 01:18:55.080 I actually 01:18:55.080 --> 01:18:55.400 think it'd be 01:18:55.400 --> 01:18:56.320 cool to set up 01:18:56.320 --> 01:18:56.740 some type of 01:18:56.740 --> 01:18:57.540 flashlight Morse 01:18:57.540 --> 01:18:58.120 code system. 01:18:59.220 --> 01:18:59.540 That'd be 01:18:59.540 --> 01:19:00.000 pretty sweet. 01:19:00.100 --> 01:19:00.400 It wouldn't 01:19:00.400 --> 01:19:00.860 be hard. 01:19:01.560 --> 01:19:02.040 I'm sure it 01:19:02.040 --> 01:19:02.400 wouldn't be. 01:19:02.400 --> 01:19:08.220 I guess 01:19:08.220 --> 01:19:08.420 we're going 01:19:08.420 --> 01:19:08.700 to shout 01:19:08.700 --> 01:19:09.080 shouts. 01:19:09.340 --> 01:19:09.860 Who has 01:19:09.860 --> 01:19:10.120 shouts? 01:19:12.920 --> 01:19:13.500 Shouts to 01:19:13.500 --> 01:19:13.980 everybody. 01:19:15.280 --> 01:19:15.800 Shouts to 01:19:15.800 --> 01:19:16.200 everybody in 01:19:16.200 --> 01:19:17.460 IRC and 01:19:17.460 --> 01:19:18.120 everybody who's 01:19:18.120 --> 01:19:18.620 always helping 01:19:18.620 --> 01:19:19.080 me with all 01:19:19.080 --> 01:19:19.520 my code 01:19:19.520 --> 01:19:19.920 rage, 01:19:20.460 --> 01:19:20.960 especially 01:19:20.960 --> 01:19:21.360 Ali, 01:19:21.440 --> 01:19:22.620 A-A-L-I, 01:19:22.820 --> 01:19:23.460 in IRC. 01:19:23.680 --> 01:19:24.760 He's been a 01:19:24.760 --> 01:19:25.240 big help with 01:19:25.240 --> 01:19:25.620 a lot of the 01:19:25.620 --> 01:19:25.960 code that's 01:19:25.960 --> 01:19:26.240 been going 01:19:26.240 --> 01:19:26.460 through. 01:19:26.560 --> 01:19:26.740 So a 01:19:26.740 --> 01:19:27.220 special thank 01:19:27.220 --> 01:19:27.660 you to 01:19:27.660 --> 01:19:28.620 that fine 01:19:28.620 --> 01:19:28.920 gentleman. 01:19:29.680 --> 01:19:29.900 Yes, 01:19:29.940 --> 01:19:30.580 Ali is a 01:19:30.580 --> 01:19:31.060 nice person 01:19:31.060 --> 01:19:31.480 and he always 01:19:31.480 --> 01:19:31.800 seems to be 01:19:31.800 --> 01:19:32.280 very helpful 01:19:32.280 --> 01:19:33.240 for Dr. 01:19:33.300 --> 01:19:33.800 Zygmunt and 01:19:33.800 --> 01:19:34.760 his rams 01:19:34.760 --> 01:19:35.280 and raves. 01:19:39.400 --> 01:19:40.000 I'll send 01:19:40.000 --> 01:19:40.560 shouts out. 01:19:40.660 --> 01:19:40.820 Oh, 01:19:40.860 --> 01:19:41.000 you know, 01:19:41.060 --> 01:19:41.380 another 01:19:41.380 --> 01:19:41.800 announcement, 01:19:42.200 --> 01:19:42.600 I guess. 01:19:43.220 --> 01:19:43.840 We're kind 01:19:43.840 --> 01:19:44.100 of going 01:19:44.100 --> 01:19:44.460 back to 01:19:44.460 --> 01:19:45.440 Linux World 01:19:45.440 --> 01:19:52.160 is coming 01:19:52.160 --> 01:19:53.000 up in 01:19:53.000 --> 01:19:53.420 Boston. 01:19:53.680 --> 01:19:54.240 I believe 01:19:54.240 --> 01:19:54.500 you can 01:19:54.500 --> 01:19:54.940 actually still 01:19:54.940 --> 01:19:55.200 get in 01:19:55.200 --> 01:19:55.660 free if 01:19:55.660 --> 01:19:56.060 you sign 01:19:56.060 --> 01:19:56.500 up now. 01:19:56.940 --> 01:19:57.220 However, 01:19:57.380 --> 01:19:58.000 the clock 01:19:58.000 --> 01:19:58.560 is ticking 01:19:58.560 --> 01:19:58.880 and I 01:19:58.880 --> 01:19:59.300 believe it 01:19:59.300 --> 01:19:59.820 will end 01:19:59.820 --> 01:20:00.500 this week 01:20:00.500 --> 01:20:00.820 as the 01:20:00.820 --> 01:20:01.260 free sign 01:20:01.260 --> 01:20:01.420 up. 01:20:01.800 --> 01:20:02.420 I'll be 01:20:02.420 --> 01:20:02.780 there. 01:20:03.120 --> 01:20:03.420 Various 01:20:03.420 --> 01:20:03.840 people from 01:20:03.840 --> 01:20:04.100 Boston 01:20:04.100 --> 01:20:04.740 2600 will 01:20:04.740 --> 01:20:05.220 be there. 01:20:06.980 --> 01:20:07.660 Just stop 01:20:07.660 --> 01:20:08.020 on by. 01:20:08.120 --> 01:20:08.320 If you're 01:20:08.320 --> 01:20:08.620 going to be 01:20:08.620 --> 01:20:08.780 in the 01:20:08.780 --> 01:20:08.980 area, 01:20:09.100 --> 01:20:09.540 just give 01:20:09.540 --> 01:20:09.740 me a 01:20:09.740 --> 01:20:10.020 ring or 01:20:10.020 --> 01:20:10.280 something. 01:20:11.640 --> 01:20:12.340 Email me 01:20:12.340 --> 01:20:12.860 actually because 01:20:12.860 --> 01:20:13.120 all my 01:20:13.120 --> 01:20:13.400 phone is 01:20:13.400 --> 01:20:13.760 messed up 01:20:13.760 --> 01:20:14.060 because 01:20:14.060 --> 01:20:14.780 asterisk is 01:20:14.780 --> 01:20:15.240 sucking. 01:20:15.240 --> 01:20:18.660 I don't 01:20:18.660 --> 01:20:19.360 shout out to 01:20:19.360 --> 01:20:19.560 Dr. 01:20:19.620 --> 01:20:20.140 for coming 01:20:20.140 --> 01:20:20.500 up on 01:20:20.500 --> 01:20:20.980 this topic 01:20:20.980 --> 01:20:22.020 with short 01:20:22.020 --> 01:20:22.360 notice. 01:20:23.360 --> 01:20:24.560 When you're 01:20:24.560 --> 01:20:25.120 getting married, 01:20:25.300 --> 01:20:25.940 your weekends 01:20:25.940 --> 01:20:26.420 really start 01:20:26.420 --> 01:20:27.000 going downhill 01:20:27.000 --> 01:20:27.300 very, 01:20:27.380 --> 01:20:27.760 very quick. 01:20:30.760 --> 01:20:31.340 Side of 01:20:31.340 --> 01:20:31.720 the week. 01:20:32.260 --> 01:20:33.020 Kyle L. 01:20:33.140 --> 01:20:33.680 posted this 01:20:33.680 --> 01:20:34.320 in IRC 01:20:34.320 --> 01:20:34.640 today. 01:20:34.820 --> 01:20:36.740 I was 01:20:36.740 --> 01:20:37.380 morbidly 01:20:37.380 --> 01:20:38.260 fascinated by 01:20:38.260 --> 01:20:38.400 it. 01:20:38.400 --> 01:20:38.740 It's 01:20:38.740 --> 01:20:39.060 called 01:20:39.060 --> 01:20:44.860 www.mydeathspace.com 01:20:44.860 --> 01:20:45.160 and it's 01:20:45.160 --> 01:20:45.780 people who 01:20:45.780 --> 01:20:46.460 have died 01:20:46.460 --> 01:20:46.860 in their 01:20:46.860 --> 01:20:47.640 MySpaces. 01:20:47.640 --> 01:20:51.020 www.mydeathspace.com 01:20:51.020 --> 01:20:53.640 It's a lot 01:20:53.640 --> 01:20:54.320 like a car 01:20:54.320 --> 01:20:54.540 wreck. 01:20:54.760 --> 01:20:55.260 You're 01:20:55.260 --> 01:20:55.800 looking at 01:20:55.800 --> 01:20:56.560 it and 01:20:56.560 --> 01:20:57.060 you're kind 01:20:57.060 --> 01:20:58.840 of disgusted 01:20:58.840 --> 01:20:59.340 by it but 01:20:59.340 --> 01:20:59.620 you just 01:20:59.620 --> 01:21:00.040 can't look 01:21:00.040 --> 01:21:00.400 away. 01:21:02.380 --> 01:21:03.320 It's weird. 01:21:03.560 --> 01:21:03.840 It really 01:21:03.840 --> 01:21:04.160 is. 01:21:04.260 --> 01:21:04.840 It's kind 01:21:04.840 --> 01:21:05.280 of eerie. 01:21:08.840 --> 01:21:09.860 Email us 01:21:09.860 --> 01:21:10.580 at 01:21:10.580 --> 01:21:11.960 www.radioatbinrev.com 01:21:11.960 --> 01:21:13.100 or voicemail 01:21:13.100 --> 01:21:13.840 us at 01:21:13.840 --> 01:21:14.740 www.lake9binrev.com 01:21:14.740 --> 01:21:15.580 Yeah, 01:21:15.680 --> 01:21:17.620 www.lake9binrev.com 01:21:17.620 --> 01:21:18.480 So leave us a 01:21:18.480 --> 01:21:18.880 voicemail. 01:21:18.980 --> 01:21:19.480 Give us a call. 01:21:19.540 --> 01:21:20.060 We actually did 01:21:20.060 --> 01:21:20.620 have a voicemail 01:21:20.620 --> 01:21:21.120 botched for a 01:21:21.120 --> 01:21:21.640 while and I 01:21:21.640 --> 01:21:21.940 think one 01:21:21.940 --> 01:21:22.520 person used 01:21:22.520 --> 01:21:23.620 it but hey 01:21:23.620 --> 01:21:24.220 you know if 01:21:24.220 --> 01:21:24.780 you're too 01:21:24.780 --> 01:21:25.540 lazy or you 01:21:25.540 --> 01:21:27.300 it's 2am 01:21:27.300 --> 01:21:28.080 you're not 01:21:28.080 --> 01:21:28.520 wearing any 01:21:28.520 --> 01:21:28.960 pants and 01:21:28.960 --> 01:21:29.280 you're thinking 01:21:29.280 --> 01:21:29.860 of us hey 01:21:29.860 --> 01:21:30.280 just give us 01:21:30.280 --> 01:21:30.720 a call and 01:21:30.720 --> 01:21:31.240 leave us a 01:21:31.240 --> 01:21:31.480 voicemail. 01:21:33.120 --> 01:21:33.720 We have 01:21:33.720 --> 01:21:34.200 closed music 01:21:34.200 --> 01:21:34.440 tonight. 01:21:34.520 --> 01:21:34.920 Our closed 01:21:34.920 --> 01:21:35.460 music tonight 01:21:35.460 --> 01:21:35.940 is the 01:21:35.940 --> 01:21:38.000 Zelda 64 01:21:38.000 --> 01:21:38.920 Orkiana 01:21:38.920 --> 01:21:39.960 I can't 01:21:39.960 --> 01:21:40.660 pronounce this 01:21:40.660 --> 01:21:41.140 Orkina 01:21:41.140 --> 01:21:41.760 Ocarina 01:21:41.760 --> 01:21:43.460 Ocarina 01:21:43.460 --> 01:21:44.240 Hey 01:21:44.240 --> 01:21:45.400 Ocarina 01:21:45.400 --> 01:21:45.780 I think I 01:21:45.780 --> 01:21:46.060 made that 01:21:46.060 --> 01:21:46.460 joke last 01:21:46.460 --> 01:21:46.600 time. 01:21:47.620 --> 01:21:48.340 Ocarina of 01:21:48.340 --> 01:21:48.740 Time 01:21:48.740 --> 01:21:49.360 Prayer. 01:21:50.420 --> 01:21:51.280 The Ocarina 01:21:51.280 --> 01:21:51.700 of Time 01:21:51.700 --> 01:21:52.000 what? 01:21:53.660 --> 01:21:54.180 Prayer. 01:21:54.560 --> 01:21:54.820 Ah, 01:21:54.960 --> 01:21:55.200 okay. 01:21:56.480 --> 01:21:57.520 It had a 01:21:57.520 --> 01:21:57.880 nice beat. 01:21:57.920 --> 01:21:58.300 I kind of 01:21:58.300 --> 01:21:58.660 liked it. 01:21:58.760 --> 01:22:01.080 It sounded 01:22:01.080 --> 01:22:01.460 nice. 01:22:01.700 --> 01:22:02.080 You should get 01:22:02.080 --> 01:22:02.720 the Boolean of 01:22:02.720 --> 01:22:03.640 Fire next time. 01:22:04.240 --> 01:22:04.440 Yeah. 01:22:05.080 --> 01:22:05.500 So, 01:22:05.720 --> 01:22:06.380 next week 01:22:06.380 --> 01:22:08.340 hopefully we 01:22:08.340 --> 01:22:08.820 don't have all 01:22:08.820 --> 01:22:09.420 these issues and 01:22:09.420 --> 01:22:09.820 we'll actually 01:22:09.820 --> 01:22:11.360 have an episode 01:22:11.360 --> 01:22:12.100 that doesn't 01:22:12.100 --> 01:22:12.660 suck as bad. 01:22:13.160 --> 01:22:13.780 We'll see you 01:22:13.780 --> 01:22:14.260 next week. 01:22:14.360 --> 01:22:14.780 Same Hack 01:22:14.780 --> 01:22:15.380 time. 01:22:15.460 --> 01:22:16.780 Especially 01:22:16.780 --> 01:22:17.660 time. 01:22:17.660 --> 01:22:17.860 Bye. 01:22:17.860 --> 01:22:17.960 Bye. 01:22:18.660 --> 01:22:18.740 Bye. 01:22:20.860 --> 01:22:21.420 Bye. 01:22:21.420 --> 01:22:21.440 Bye. 01:22:23.940 --> 01:22:24.740 Bye. 01:22:24.740 --> 01:22:25.120 Bye. 01:22:25.120 --> 01:22:25.460 Bye. 01:22:25.460 --> 01:22:25.660 Bye. 01:22:25.840 --> 01:22:25.900 Bye. 01:22:25.920 --> 01:22:25.980 Bye. 01:22:25.980 --> 01:22:27.920 Bye. 01:22:29.300 --> 01:22:29.700 Bye. 01:22:29.700 --> 01:22:30.240 Bye. 01:22:30.640 --> 01:22:31.440 Bye. 01:22:32.040 --> 01:22:32.100 Bye. 01:22:32.100 --> 01:22:32.580 Bye. 01:22:32.580 --> 01:22:34.900 Bye. 01:22:35.140 --> 01:22:36.160 Bye. 01:22:36.160 --> 01:22:36.720 Bye. 01:22:41.360 --> 01:22:41.800 Bye. 01:22:41.860 --> 01:22:42.000 Bye. 01:22:42.360 --> 01:22:43.020 Bye. 01:22:43.120 --> 01:22:43.520 Bye. 01:22:43.520 --> 01:22:43.760 Bye. 01:22:43.760 --> 01:22:44.300 Bye. 01:22:44.300 --> 01:23:14.280 Thank you. 01:23:14.300 --> 01:23:44.280 Thank you. 01:23:44.300 --> 01:24:14.280 Thank you. 01:24:14.300 --> 01:24:44.280 Thank you. 01:24:44.300 --> 01:25:14.280 Thank you. 01:25:14.300 --> 01:25:44.280 Thank you. 01:25:44.300 --> 01:26:14.280 Thank you. 01:26:14.300 --> 01:26:44.280 Thank you. 01:26:44.300 --> 01:27:14.280 Thank you.